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Improved erythroid differentiation of multiple human pluripotent stem cell lines in microcarrier culture by modulation of Wnt/β-Catenin signaling.

作者信息

Sivalingam Jaichandran, Chen Hong Yu, Yang Bin-Xia, Lim Zhong Ri, Lam Alan Tin Lun, Woo Tsung Liang, Chen Allen Kuan-Liang, Reuveny Shaul, Loh Yuin-Han, Oh Steve Kah-Weng

机构信息

Stem Cell Group, Bioprocessing Technology Institute, Agency for Science, Technology and Research, Republic of Singapore

Institute of Molecular and Cellular Biology, Agency for Science, Technology and Research, Republic of Singapore.

出版信息

Haematologica. 2018 Jul;103(7):e279-e283. doi: 10.3324/haematol.2017.180919. Epub 2018 Mar 8.

DOI:10.3324/haematol.2017.180919
PMID:29519863
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6029542/
Abstract
摘要

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2
Integrated processes for expansion and differentiation of human pluripotent stem cells in suspended microcarriers cultures.用于在悬浮微载体培养物中扩增和分化人多能干细胞的整合方法。
Biochem Biophys Res Commun. 2016 May 6;473(3):764-8. doi: 10.1016/j.bbrc.2015.09.079. Epub 2015 Sep 15.
3
Developing Defined and Scalable 3D Culture Systems for Culturing Human Pluripotent Stem Cells at High Densities.开发用于高密度培养人类多能干细胞的明确且可扩展的3D培养系统。
Cell Mol Bioeng. 2014 Jun;7(2):172-183. doi: 10.1007/s12195-014-0333-z.
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An intermittent rocking platform for integrated expansion and differentiation of human pluripotent stem cells to cardiomyocytes in suspended microcarrier cultures.一种用于在悬浮微载体培养中实现人多能干细胞向心肌细胞整合性扩增与分化的间歇性摇摆平台。
Stem Cell Res. 2014 Sep;13(2):202-13. doi: 10.1016/j.scr.2014.06.002. Epub 2014 Jun 27.
5
Wnt signaling controls the specification of definitive and primitive hematopoiesis from human pluripotent stem cells.Wnt 信号通路控制着人类多能干细胞向定型和原始造血的分化。
Nat Biotechnol. 2014 Jun;32(6):554-61. doi: 10.1038/nbt.2915. Epub 2014 May 18.
6
3D microcarrier system for efficient differentiation of human pluripotent stem cells into hematopoietic cells without feeders and serum [corrected].无饲养层和血清条件下高效分化人多能干细胞为造血细胞的 3D 微载体系统 [已更正]。
Regen Med. 2013 Jul;8(4):413-24. doi: 10.2217/rme.13.36.
7
RUNX1a enhances hematopoietic lineage commitment from human embryonic stem cells and inducible pluripotent stem cells.RUNX1a 增强了人类胚胎干细胞和诱导多能干细胞向造血谱系的定向分化。
Blood. 2013 Apr 11;121(15):2882-90. doi: 10.1182/blood-2012-08-451641. Epub 2013 Jan 31.
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