Jilly Ruven, Khan Nadir Zaman, Aronsson Henrik, Schneider Dirk
Institute of Pharmacy and Biochemistry, Johannes Gutenberg University Mainz, Mainz, Germany.
Department of Biotechnology, University of Malakand, Malakand, Pakistan.
Front Plant Sci. 2018 Feb 22;9:206. doi: 10.3389/fpls.2018.00206. eCollection 2018.
Dynamin-like proteins (DLPs) are a family of membrane-active proteins with low sequence identity. The proteins operate in different organelles in eukaryotic cells, where they trigger vesicle formation, membrane fusion, or organelle division. As discussed here, representatives of this protein family have also been identified in chloroplasts and DLPs are very common in cyanobacteria. Since cyanobacteria and chloroplasts, an organelle of bacterial origin, have similar internal membrane systems, we suggest that DLPs are involved in membrane dynamics in cyanobacteria and chloroplasts. Here, we discuss the features and activities of DLPs with a focus on their potential presence and activity in chloroplasts and cyanobacteria.
类发动蛋白(DLPs)是一类膜活性蛋白家族,其序列相似性较低。这些蛋白在真核细胞的不同细胞器中发挥作用,在那里它们引发囊泡形成、膜融合或细胞器分裂。如本文所讨论的,该蛋白家族的代表也已在叶绿体中被鉴定出来,并且DLPs在蓝细菌中非常常见。由于蓝细菌和叶绿体(一种起源于细菌的细胞器)具有相似的内膜系统,我们认为DLPs参与了蓝细菌和叶绿体中的膜动态变化。在这里,我们讨论DLPs的特征和活性,重点关注它们在叶绿体和蓝细菌中的潜在存在和活性。