Padfield N L
Ann R Coll Surg Engl. 1987 Jan;69(1):16-7.
Severe difficulties were encountered when a 47 year old man, with symptomatic carcinoid pretreated with ketanserin 80 mg twice daily was anaesthetised for hepatic arterial embolisation. The same patient, having had three days pretreatment with parachlorophenylalanine 500 mg four times daily and cyproheptadine 4 mg three times daily in addition to the ketanserin, was anaesthetised a week later without any difficulties. On the second occasion much better symptom control had been achieved. It is suggested that pretreatment with ketanserin alone is insufficient in severely symptomatic carcinoid and that the best possible medical control of symptoms should be achieved before anaesthesia.
一名47岁患有类癌综合征的男性患者，每天两次服用80毫克酮色林进行预处理，在接受肝动脉栓塞麻醉时遇到了严重困难。同一患者，除了服用酮色林外，每天四次服用500毫克对氯苯丙氨酸、每天三次服用4毫克赛庚啶进行了三天预处理，一周后进行麻醉时没有遇到任何困难。第二次时症状得到了更好的控制。有人认为，对于症状严重的类癌综合征，仅用酮色林预处理是不够的，在麻醉前应尽可能实现最佳的症状药物控制。
