Eisenkraft J B, Dimich I, Miller R
Anaesthesia. 1981 Sep;36(9):881-5. doi: 10.1111/j.1365-2044.1981.tb08862.x.
The use of ketamine in patients with carcinoid syndrome is controversial because of the catecholamine response to this agent. Prior administration of diazepam modifies the catecholamine response to ketamine and may make its use in such patients safe. The successful use of a diazepam-ketamine technique for anaesthesia of a patient with malignant carcinoid syndrome and associated tricuspid valve disease who underwent laparotomy and hepatic artery ligation is described. The theoretical advantages of safe ketamine anaesthesia in carcinoid patients are discussed and the relevant literature reviewed. To the authors' knowledge the successful use of ketamine anaesthesia in carcinoid syndrome has not previously been reported.
由于儿茶酚胺对氯胺酮的反应，在类癌综合征患者中使用氯胺酮存在争议。预先给予地西泮可改变儿茶酚胺对氯胺酮的反应，并可能使其在这类患者中的使用变得安全。本文描述了地西泮-氯胺酮技术成功用于一名患有恶性类癌综合征及相关三尖瓣疾病的患者的麻醉，该患者接受了剖腹手术和肝动脉结扎术。讨论了类癌患者安全使用氯胺酮麻醉的理论优势，并对相关文献进行了综述。据作者所知，此前尚未有关于在类癌综合征中成功使用氯胺酮麻醉的报道。
