Department of Dentistry, Jinnah Postgraduate Medical Centre, Karachi, Pakistan.
Department of Prosthetic Dental Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
J Periodontol. 2018 May;89(5):571-576. doi: 10.1002/JPER.17-0495.
It is hypothesized that (a) self-perceived oral symptoms (OSs) are worse in intravenous heroin addicts (IHA) than controls; and (b) clinical periodontal inflammatory parameters (plaque index [PI], bleeding on probing [BOP], PD and clinical attachment loss [AL]), number of missing teeth (MT), and radiographic marginal bone loss (MBL) are higher in IHA compared with controls. The aim was to compare the self-perceived OSs and periodontal parameters among young IHA and controls.
Sociodemographic data, self-perceived OSs and duration and daily frequency of intravenous heroin use was gathered using a structured questionnaire. Full-mouth PI, BOP, PD, and clinical AL were measured, and number of MT were recorded. Mesial and distal MBL on all teeth was measured on digital radiographs. Odds ratios (OR) with 95% confidence intervals (CI) were computed for self-perceived OSs and periodontal parameters were assessed using the Mann Whitney U-test and logistic regression analysis. Sample-size was estimated, and level of significance was set at P < 0.05.
OR (95% CI) for self-perceived loose teeth (P < 0.001), pain in teeth (P < 0.001), dry mouth (P < 0.001), burning sensation in mouth (P < 0.001), bleeding gums (P < 0.001) and pain during chewing (P < 0.001) were significantly higher in the test than control group. Number of MT (P < 0.05), PI (P < 0.05), clinical AL (P < 0.05), and mesial (P < 0.05) and distal (P < 0.05) MBL were statistically significantly higher among individuals in the test group compared with the control group.
Self-perceived OSs and periodontal inflammatory parameters were worse in IHA than controls.
据推测，（a）静脉内海洛因成瘾者（IHA）比对照组自我感知的口腔症状（OSs）更差；（b）临床牙周炎症参数（菌斑指数[PI]、探诊出血[BOP]、PD 和临床附着丧失[AL]）、缺失牙数（MT）和放射状边缘骨丧失（MBL）在 IHA 中比对照组更高。目的是比较年轻的 IHA 和对照组之间的自我感知 OSs 和牙周参数。
使用结构化问卷收集社会人口统计学数据、自我感知 OSs 以及静脉内海洛因使用的持续时间和每日频率。测量全口 PI、BOP、PD 和临床 AL，并记录 MT 数量。在所有牙齿的数字射线照片上测量近中和远中 MBL。使用 Mann-Whitney U 检验评估自我感知 OSs 和牙周参数，使用逻辑回归分析评估比值比（OR）和 95%置信区间（CI）。估计样本量，显著性水平设为 P < 0.05。
自我感知牙齿松动（P < 0.001）、牙齿疼痛（P < 0.001）、口干（P < 0.001）、口腔烧灼感（P < 0.001）、牙龈出血（P < 0.001）和咀嚼时疼痛（P < 0.001）的 OR（95%CI）在测试组中明显高于对照组。MT 数量（P < 0.05）、PI（P < 0.05）、临床 AL（P < 0.05）以及近中（P < 0.05）和远中（P < 0.05）MBL 在测试组中明显高于对照组。
IHA 比对照组自我感知的口腔症状和牙周炎症参数更差。
