Lewis Douglas, Blow Andrew, Tye Jonathan, Hew-Butler Tamara
Family and Community Medicine, Via Christi Health System, Wichita, Kansas, USA.
Precision Hydration, Christchurch, UK.
BMJ Case Rep. 2018 Mar 9;2018:bcr-2017-222916. doi: 10.1136/bcr-2017-222916.
Exercise-associated hyponatraemia (EAH) always involves a component of overhydration relative to available exchangeable sodium stores. In the majority of cases, this is purely due to excessive consumption of fluids during exercise. In a lesser number of cases, it is apparent that excessive sodium loss through sweat may play a role by decreasing the amount of acutely available exchangeable sodium. Two cases demonstrating the latter, one in an individual with cystic fibrosis (CF) and another in an endurance athlete without CF, demonstrate how elevated dermal sweat losses may contribute to a dilutional EAH along a pathophysiological continuum.
运动相关性低钠血症(EAH)总是涉及相对于可用可交换钠储备的水合过度成分。在大多数情况下,这纯粹是由于运动期间液体摄入过多所致。在少数情况下,显然通过汗液过度丢失钠可能通过减少急性可用可交换钠的量而发挥作用。两个病例说明了后者,一个是患有囊性纤维化(CF)的个体,另一个是没有CF的耐力运动员,这两个病例展示了皮肤汗液损失增加如何沿着病理生理连续体导致稀释性EAH。