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[阴茎癌:诊断与分期]

[Penile cancer: diagnosis and staging].

作者信息

Sievert K-D, Dräger D-L, Köhn F-M, Milerski S, Protzel C, Hakenberg O W

机构信息

Urologische Klinik und Poliklinik, Universitätsmedizin Rostock, Ernst-Heydemann-Str. 6, 18057, Rostock, Deutschland.

Andrologicum München, München, Deutschland.

出版信息

Urologe A. 2018 Apr;57(4):418-422. doi: 10.1007/s00120-018-0602-x.

DOI:10.1007/s00120-018-0602-x
PMID:29523915
Abstract

Penile cancer is often an obvious visual diagnosis but histologic verification should be obtained prior to treatment. The clinical examination should determine the tumor stage and whether it has infiltrated the cavernous bodies and/or the urethra and it should adequately assess the inguinal lymph nodes. Preoperative imaging of the lesion is only indicated in equivocal cases. Curative treatment requires the complete removal of the primary tumor and all metastatic lymph nodes. Lymph node management is the key prognostic factor in the treatment of penile cancer. No imagining technique such as the ultrasound, CT, MRI or PET/CT is able to adequately detect micrometastatic lymph nodes. Therefore, invasive (inguinal) lymph node diagnosis is indicated for all tumour stages from pT1G2. Over 90% of penile cancer cases can be cured with early diagnosis and adequate treatment if routine self-examination and physical examinations are regularly performed.

摘要

阴茎癌通常通过肉眼即可明显诊断,但在治疗前应进行组织学验证。临床检查应确定肿瘤分期,以及它是否已浸润海绵体和/或尿道,并应充分评估腹股沟淋巴结。仅在诊断不明确的病例中才需要对病变进行术前影像学检查。根治性治疗需要完全切除原发性肿瘤和所有转移性淋巴结。淋巴结处理是阴茎癌治疗中的关键预后因素。没有任何成像技术,如超声、CT、MRI或PET/CT能够充分检测出微转移淋巴结。因此,对于所有pT1G2及以上的肿瘤分期,均需进行有创(腹股沟)淋巴结诊断。如果定期进行常规自我检查和体格检查,超过90%的阴茎癌病例可通过早期诊断和适当治疗得以治愈。

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Nuklearmedizin. 2018 Feb;57(1):26-30. doi: 10.3412/Nukmed-0932-17-10. Epub 2018 Feb 21.
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[Human papillomavirus and penile cancer : Thinking about measures for prevention].[人乳头瘤病毒与阴茎癌:关于预防措施的思考]
Urologe A. 2018 Apr;57(4):413-417. doi: 10.1007/s00120-018-0597-3.
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Pseudoepitheliomatous keratotic and micaceous balanitis treated with topical 5-fluorouracil and liquid nitrogen.
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Clin Transl Oncol. 2022 Feb;24(2):331-341. doi: 10.1007/s12094-021-02694-7. Epub 2021 Aug 27.
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Human papilloma virus: A review study of epidemiology, carcinogenesis, diagnostic methods, and treatment of all HPV-related cancers.人乳头瘤病毒:一项关于所有与人乳头瘤病毒相关癌症的流行病学、致癌机制、诊断方法及治疗的综述研究
Med J Islam Repub Iran. 2021 May 22;35:65. doi: 10.47176/mjiri.35.65. eCollection 2021.
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Secondary NK/T cell lymphoma after radiotherapy for non-HPV-related squamous cell carcinoma of the penis: an early warning event and literature review.阴茎非HPV相关鳞状细胞癌放疗后发生的继发性NK/T细胞淋巴瘤:一个预警事件及文献综述
Int J Clin Exp Pathol. 2020 Aug 1;13(8):2173-2180. eCollection 2020.
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Clin Exp Dermatol. 2017 Jun;42(4):424-426. doi: 10.1111/ced.13072. Epub 2017 Apr 13.
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