模拟真核电压门控钠通道NaPaS的离子渗透和离子选择。 - Suppr

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Simulating the ion permeation and ion selection for a eukaryotic voltage-gated sodium channel NaPaS.

作者信息

Zhang Juanrong, Mao Wenzhi, Ren Yanhui, Sun Rui-Ning, Yan Nieng, Gong Haipeng

机构信息

MOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua University, Beijing, 100084, China.

Beijing Advanced Innovation Center for Structural Biology, Tsinghua University, Beijing, 100084, China.

出版信息

Protein Cell. 2018 Jun;9(6):580-585. doi: 10.1007/s13238-018-0522-y.

DOI:10.1007/s13238-018-0522-y

PMID:29532417

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5966359/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f40/5966359/9ecf8ccb6112/13238_2018_522_Fig1_HTML.jpg

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Simulating the ion permeation and ion selection for a eukaryotic voltage-gated sodium channel NaPaS.

作者信息

Zhang Juanrong, Mao Wenzhi, Ren Yanhui, Sun Rui-Ning, Yan Nieng, Gong Haipeng

机构信息

MOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua University, Beijing, 100084, China.

Beijing Advanced Innovation Center for Structural Biology, Tsinghua University, Beijing, 100084, China.

出版信息

Protein Cell. 2018 Jun;9(6):580-585. doi: 10.1007/s13238-018-0522-y.

DOI:10.1007/s13238-018-0522-y

PMID:29532417

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5966359/

Abstract

摘要

相似文献

Simulating the ion permeation and ion selection for a eukaryotic voltage-gated sodium channel NaPaS.

Protein Cell. 2018 Jun;9(6):580-585. doi: 10.1007/s13238-018-0522-y.

The mechanism of Na⁺/K⁺ selectivity in mammalian voltage-gated sodium channels based on molecular dynamics simulation.

Biophys J. 2013 Jun 4;104(11):2401-9. doi: 10.1016/j.bpj.2013.04.035.

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Curr Top Membr. 2016;78:215-60. doi: 10.1016/bs.ctm.2016.07.005. Epub 2016 Aug 3.

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Protein Cell. 2015 Jun;6(6):413-22. doi: 10.1007/s13238-015-0152-6. Epub 2015 Apr 17.

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Channels (Austin). 2016;10(3):225-37. doi: 10.1080/19336950.2016.1148224. Epub 2016 Feb 6.

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Biochim Biophys Acta Biomembr. 2017 May;1859(5):879-887. doi: 10.1016/j.bbamem.2017.02.003. Epub 2017 Feb 8.

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Cell Res. 2013 Mar;23(3):409-22. doi: 10.1038/cr.2012.173. Epub 2012 Dec 18.

引用本文的文献

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Front Pharmacol. 2024 Apr 25;15:1378315. doi: 10.3389/fphar.2024.1378315. eCollection 2024.

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Channels (Austin). 2024 Dec;18(1):2287832. doi: 10.1080/19336950.2023.2287832. Epub 2023 Nov 30.

The modes of action of ion-channel-targeting neurotoxic insecticides: lessons from structural biology.

Nat Struct Mol Biol. 2023 Oct;30(10):1411-1427. doi: 10.1038/s41594-023-01113-5. Epub 2023 Oct 16.

Molecular Dynamics Simulations of Ion Permeation in Human Voltage-Gated Sodium Channels.

J Chem Theory Comput. 2023 May 23;19(10):2953-2972. doi: 10.1021/acs.jctc.2c00990. Epub 2023 Apr 28.

Simulation and Machine Learning Methods for Ion-Channel Structure Determination, Mechanistic Studies and Drug Design.

Front Pharmacol. 2022 Jun 28;13:939555. doi: 10.3389/fphar.2022.939555. eCollection 2022.

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Front Pharmacol. 2022 Mar 17;13:858348. doi: 10.3389/fphar.2022.858348. eCollection 2022.

Interactions of Sea Anemone Toxins with Insect Sodium Channel-Insights from Electrophysiology and Molecular Docking Studies.

Molecules. 2021 Feb 28;26(5):1302. doi: 10.3390/molecules26051302.

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本文引用的文献

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Drug Des Devel Ther. 2017 Aug 4;11:2301-2324. doi: 10.2147/DDDT.S133944. eCollection 2017.

Structure of the Na1.4-β1 Complex from Electric Eel.

Cell. 2017 Jul 27;170(3):470-482.e11. doi: 10.1016/j.cell.2017.06.039. Epub 2017 Jul 20.

Structure of a eukaryotic voltage-gated sodium channel at near-atomic resolution.

Science. 2017 Mar 3;355(6328). doi: 10.1126/science.aal4326. Epub 2017 Feb 9.

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PLoS One. 2015 Aug 14;10(8):e0133000. doi: 10.1371/journal.pone.0133000. eCollection 2015.

Theoretical and simulation studies on voltage-gated sodium channels.

Protein Cell. 2015 Jun;6(6):413-22. doi: 10.1007/s13238-015-0152-6. Epub 2015 Apr 17.

The mechanism of Na⁺/K⁺ selectivity in mammalian voltage-gated sodium channels based on molecular dynamics simulation.

Biophys J. 2013 Jun 4;104(11):2401-9. doi: 10.1016/j.bpj.2013.04.035.

Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing.

Nat Commun. 2012;3:1102. doi: 10.1038/ncomms2077.

Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel.

Nature. 2012 May 20;486(7401):130-4. doi: 10.1038/nature11054.

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Nature. 2011 Jul 10;475(7356):353-8. doi: 10.1038/nature10238.

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