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Ro 15 - 8074、Ro 19 - 5247、A - 56268及罗红霉素(RU 28965)对淋病奈瑟菌和沙眼衣原体的体外活性。

In vitro activity of Ro 15-8074, Ro 19-5247, A-56268, and roxithromycin (RU 28965) against Neisseria gonorrhoeae and Chlamydia trachomatis.

作者信息

Bowie W R, Shaw C E, Chan D G, Black W A

出版信息

Antimicrob Agents Chemother. 1987 Mar;31(3):470-2. doi: 10.1128/AAC.31.3.470.

Abstract

In vitro Ro 15-8074 and Ro 19-5247 (T2525), two new oral cephalosporins, were active against 410 penicillin-susceptible and -resistant isolates of Neisseria gonorrhoeae. Two new macrolides, A-56268 and to a lesser extent roxithromycin (RU 28965), were active against Chlamydia trachomatis. A-56268 had activity against N. gonorrhoeae similar to that of erythromycin.

摘要

新型口服头孢菌素Ro 15 - 8074和Ro 19 - 5247(T2525)在体外对410株青霉素敏感和耐药的淋病奈瑟菌均有活性。两种新型大环内酯类药物A - 56268以及活性稍弱的罗红霉素(RU 28965)对沙眼衣原体有活性。A - 56268对淋病奈瑟菌的活性与红霉素相似。

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