Eudesmane-Type Sesquiterpene Glycosides from Dictamnus dasycarpus Turcz.

Eudesmane-type sesquiterpenes have been reported to exhibit varieties of biological activities. During the process of investigating this kind of natural product from the root bark of Turcz., 13 eudesmane-type sesquiterpene glycosides including six new isolates, named as dictameudesmnosides A₁ (), A₂ (), B (), C (), D (), and E (), together with seven known ones (-), were obtained. Herein, their structures were determined by the analysis of physical data, spectroscopic analysis, and chemical methods. The existence of α-configuration glucose units in their structures (-, ) is not very common in natural glycosidic components. Meanwhile, compounds -, , and - displayed TG accumulation inhibitory effects on HepG2 cells.