Long Chuyan, Yu Yan, Cui Bota, Jagessar Sabreen Abdul Rahman, Zhang Jie, Ji Guozhong, Huang Guangming, Zhang Faming
Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, 121 Jiang Jia Yuan, Nanjing, 210011, China.
Key Lab of Holistic Integrative Enterology, Nanjing Medical University, 121 Jiang Jia Yuan, Nanjing, 210011, China.
BMC Gastroenterol. 2018 Mar 13;18(1):37. doi: 10.1186/s12876-018-0766-2.
This study aimed to evaluate the feasibility, safety, and value of a quick technique for transendoscopic enteral tubing (TET) through mid-gut.
A prospective interventional study was performed in a single center. A TET tube was inserted into mid-gut through the nasal orifice and fixed on the pylorus wall by one tiny titanium endoscopic clip under anesthesia. The feasibility, safety, success rate, and satisfaction with TET placement were evaluated for enteral nutrition or fecal microbiota transplantation.
A total of 86 patients underwent mid-gut TET. The success rate of the TET procedure was 98.8% (85/86). Mean tubing time of the TET procedure was 4.2 ± 1.9 min. 10 cases of procedure was enough for training of general endoscopist to shorten the procedure time (7.0 min vs 4.0 min, p < 0.05). 97.7% (84/86) of patients were satisfied with the TET placement. Procedure-related and tube-related adverse events were observed in 8.1% (7/86) and 7.0% (6/86) of patients respectively. There were no moderate to severe adverse events during tube extubation.
TET through mid-gut is a novel, convenient, reliable and safe procedure for mid-gut administration with a high degree of patient satisfaction.
This research was retrospectively registered with clinicaltrials.gov. Trial registration date: 29th November 2017.
NCT03335982 .
本研究旨在评估一种经内镜中肠置管快速技术的可行性、安全性及价值。
在单一中心进行前瞻性干预研究。在麻醉下,将一根经内镜中肠置管(TET)经鼻插入中肠,并用一个微小的钛制内镜夹固定于幽门壁。对用于肠内营养或粪便微生物群移植的TET置管的可行性、安全性、成功率及患者满意度进行评估。
共有86例患者接受了中肠TET置管。TET操作的成功率为98.8%(85/86)。TET操作的平均置管时间为4.2±1.9分钟。10例操作足以让普通内镜医师进行训练以缩短操作时间(7.0分钟对4.0分钟,p<0.05)。97.7%(84/86)的患者对TET置管感到满意。分别有8.1%(7/86)和7.0%(6/86)的患者观察到与操作相关和与置管相关的不良事件。拔管期间未出现中度至重度不良事件。
经中肠TET置管是一种用于中肠给药的新颖、便捷、可靠且安全的操作,患者满意度高。
本研究在clinicaltrials.gov进行回顾性注册。试验注册日期:2017年11月29日。
NCT03335982 。