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用于精神分裂症社会认知康复的e-MotionalTraining 1.0随机临床试验。

Randomized Clinical Trial with e-MotionalTraining 1.0 for Social Cognition Rehabilitation in Schizophrenia.

作者信息

Maroño Souto Yolanda, Vázquez Campo Miriam, Díaz Llenderrozas Francisco, Rodríguez Álvarez Marina, Mateos Raimundo, García Caballero Alejandro

机构信息

Department of Psychobiology and Clinical Psychology, Psychology School, University of Santiago de Compostela, Santiago de Compostela, Spain.

Department of Psychiatry, Instituto Biomédico Galicia Sur, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Complexo Hospitalario Universitario de Ourense, Ourense, Spain.

出版信息

Front Psychiatry. 2018 Feb 26;9:40. doi: 10.3389/fpsyt.2018.00040. eCollection 2018.

DOI:10.3389/fpsyt.2018.00040
PMID:29535646
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5834490/
Abstract

BACKGROUND

Schizophrenia patients present deficits in social cognition (SC), emotion and social perception, theory of mind (ToM), and attributional style. This study tested the efficacy, in real clinical conditions, of a online self-training program in SC, e-Motional Training, in comparison with treatment as usual.

METHOD

A randomized single-blinded multicenter clinical trial was conducted with 60 schizophrenia stable outpatients. All patients (control and intervention) were treated with drug therapy, case management, and individual and group psychotherapy (not focused on SC). Intervention group was treated with e-Motional Training, an online program devised for SC rehabilitation.

STATISTICAL ANALYSIS

A descriptive analysis and parametric/non-parametric tests were used to compare both groups at baseline. Analysis of covariance was used to compared post-pre changes in SC between the two interventions. If the group effect was significant, follow-up univariate test (-test for dependent samples) was carried out in each group to verify whether the effect was due to improvement in the intervention group or deterioration in the control group. We considered statistically significant differences with  < 0.05.

RESULTS

Significant improvements were obtained in the intervention group in emotion recognition and most ToM variables in comparison with the control group.

DISCUSSION

seems to be a promising online training tool for SC deficits in schizophrenia, covering the lack of similar intervention instruments in our community.

摘要

背景

精神分裂症患者在社会认知(SC)、情感与社会感知、心理理论(ToM)以及归因方式方面存在缺陷。本研究在实际临床环境中,测试了一种针对SC的在线自我训练项目——电子情感训练(e-Motional Training)与常规治疗相比的疗效。

方法

对60名病情稳定的精神分裂症门诊患者进行了一项随机单盲多中心临床试验。所有患者(对照组和干预组)均接受药物治疗、病例管理以及个体和团体心理治疗(不聚焦于SC)。干预组接受电子情感训练治疗,这是一个专为SC康复设计的在线项目。

统计分析

采用描述性分析和参数/非参数检验在基线时比较两组。使用协方差分析比较两种干预措施后SC的前后变化。如果组间效应显著,则在每组中进行随访单变量检验(相关样本的t检验),以验证效应是由于干预组的改善还是对照组的恶化所致。我们认为p < 0.05时有统计学显著差异。

结果

与对照组相比,干预组在情感识别和大多数ToM变量方面取得了显著改善。

讨论

对于精神分裂症患者的SC缺陷,电子情感训练似乎是一种有前景的在线训练工具,弥补了我们社区缺乏类似干预工具的不足。

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e-Motional Training®: Pilot study on a novel online training program on social cognition for patients with schizophrenia.电子情绪训练®:针对精神分裂症患者的新型社交认知在线训练项目的初步研究。
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