Sperk G, Reynolds G P, Riederer P
J Neural Transm. 1987;69(1-2):153-60. doi: 10.1007/BF01244106.
Size exclusion high performance liquid chromatography of post mortem human putamen samples revealed three somatostatin-immunoreactive peaks. The two major peaks cochromatographed with synthetic somatostatin-14 and somatostatin-28, respectively whereas the presumed somatostatin precursor preceded these peaks. In 11 samples obtained post mortem from patients suffering from Huntington's Disease somatostatin-like immunoreactivity was increased by about 55% in the mean. This increase was mainly due to increases in somatostatin-14 and--to a minor extent--of somatostatin-28, whereas the presumed precursor was not significantly changed.
对死后人体壳核样本进行的尺寸排阻高效液相色谱分析显示出三个生长抑素免疫反应峰。两个主要峰分别与合成的生长抑素 -14 和生长抑素 -28 共色谱，而推测的生长抑素前体先于这些峰出现。在从患有亨廷顿舞蹈症的患者死后获取的 11 个样本中，生长抑素样免疫反应性平均增加了约 55%。这种增加主要是由于生长抑素 -14 的增加，以及在较小程度上生长抑素 -28 的增加，而推测的前体没有显著变化。
