Piccoli Giorgina B, Alrukhaimi Mona, Liu Zhi-Hong, Zakharova Elena, Levin Adeera
Department of Clinical and Biological Sciences, University of Torino, Torino, Italy.
Nephrology, Centre Hospitalier Le Mans, Le Mans, France.
BMC Nephrol. 2018 Mar 15;19(1):66. doi: 10.1186/s12882-018-0864-y.
Chronic Kidney Disease affects approximately 10% of the world's adult population: it is within the top 20 causes of death worldwide, and its impact on patients and their families can be devastating. World Kidney Day and International Women's Day in 2018 coincide, thus offering an opportunity to reflect on the importance of women's health and specifically their kidney health, on the community, and the next generations, as well as to strive to be more curious about the unique aspects of kidney disease in women so that we may apply those learnings more broadly.Girls and women, who make up approximately 50% of the world's population, are important contributors to society and their families. Gender differences continue to exist around the world in access to education, medical care, and participation in clinical studies. Pregnancy is a unique state for women, offering an opportunity for diagnosis of kidney disease, but also a state where acute and chronic kidney diseases may manifest, and which may impact future generations with respect to kidney health. There are various autoimmune and other conditions that are more likely to impact women with profound consequences for child bearing, and on the fetus. Women have different complications on dialysis than men, and are more likely to be donors than recipients of kidney transplants.In this editorial, we focus on what we do and do not know about women, kidney health, and kidney disease, and what we might learn in the future to improve outcomes worldwide.
慢性肾脏病影响着全球约10%的成年人口：它位列全球前20大死因，对患者及其家庭的影响可能是毁灭性的。2018年世界肾脏日与国际妇女节重合，这为人们提供了一个契机，来思考女性健康尤其是她们的肾脏健康对社区和下一代的重要性，并努力对女性肾病的独特方面保持更多好奇，以便我们能更广泛地应用这些认知。女孩和女性约占世界人口的50%，她们是社会及其家庭的重要贡献者。在全球范围内，在获得教育、医疗保健以及参与临床研究方面，性别差异依然存在。怀孕对女性来说是一种独特状态，它既为诊断肾病提供了机会，但也是急性和慢性肾病可能显现的状态，并且这可能会对后代的肾脏健康产生影响。有多种自身免疫性疾病和其他病症更易影响女性，对生育及胎儿会产生深远影响。女性在透析时出现的并发症与男性不同，而且她们成为肾脏移植供体的可能性高于受体。在这篇社论中，我们聚焦于我们对女性、肾脏健康和肾病已知与未知的情况，以及我们未来为改善全球治疗效果可能学到的东西。
