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面肌痉挛对眼压测量的影响。

Effect of Hemifacial Spasm on Intraocular Pressure Measurement.

作者信息

Cicik Erdogan, Yildirim Rengin, Arici Ceyhun, Dikkaya Funda, Arslan Osman Sevki

机构信息

Department of Ophthalmology, Cerrahpasa School of Medicine, Istanbul University, Istanbul, Turkey.

Department of Ophthalmology, Medipol University Medical Faculty, Istanbul, Turkey.

出版信息

J Ophthalmol. 2018 Feb 6;2018:3621215. doi: 10.1155/2018/3621215. eCollection 2018.

Abstract

PURPOSE

To evaluate the effect of hemifacial spasm (HFS) on intraocular pressure (IOP) measurement.

METHODS

Twenty-four consecutive patients with HFS and 25 age- and gender-matched randomly selected eyes of healthy volunteers underwent corneal pachymetry and IOP measurements using Goldmann applanation tonometer (GAT) and noncontact tonometer (NCT). IOP measurements were performed before (during HFS) and 2 weeks after Botox injections in HFS patients and in healthy volunteers without Botox injections.

RESULTS

There was no statistical difference between involved eye side and uninvolved eye side of HFS patients in measured central corneal thickness. Similarly, no difference was found between involved eye side of HFS patients and controls. There were no statistically significant differences comparing IOP values before treatment and levels measured at 2 weeks of Botox injections, either with GAT ( = 0.33, 0.11) or NCT ( = 0.80, 0.43) devices in the involved eyes and uninvolved eyes of patients with HFS, respectively. There were also no significant differences in these parameters (GAT ( = 0.63) and NCT ( = 0.54)) in controls.

CONCLUSIONS

Contractions in facial muscles may not lead to significant increase in IOP in HFS patients. This result may help clinical decision making in the treatment of glaucoma patients with HFS. This trial is registered with NCT03390803.

摘要

目的

评估面肌痉挛(HFS)对眼压(IOP)测量的影响。

方法

连续纳入24例HFS患者以及25只年龄和性别匹配的随机选取的健康志愿者眼睛,使用Goldmann压平眼压计(GAT)和非接触眼压计(NCT)进行角膜测厚和眼压测量。在HFS患者以及未注射肉毒杆菌毒素的健康志愿者中,于肉毒杆菌毒素注射前(HFS发作期间)和注射后2周进行眼压测量。

结果

HFS患者患侧眼与未患侧眼测量的中央角膜厚度无统计学差异。同样,HFS患者患侧眼与对照组之间也未发现差异。分别比较HFS患者患侧眼和未患侧眼治疗前的眼压值与肉毒杆菌毒素注射2周时测量的眼压水平,使用GAT(P = 0.33,自由度 = 0.11)或NCT(P = 0.80,自由度 = 0.43)设备均无统计学显著差异。对照组在这些参数方面(GAT(P = 0.63)和NCT(P = 0.54))也无显著差异。

结论

面肌痉挛患者面部肌肉收缩可能不会导致眼压显著升高。这一结果可能有助于青光眼合并HFS患者的临床决策。本试验已在NCT03390803注册。

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Effect of Hemifacial Spasm on Intraocular Pressure Measurement.面肌痉挛对眼压测量的影响。
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Measuring intraocular pressure.测量眼压。
Curr Opin Ophthalmol. 2015 Mar;26(2):103-9. doi: 10.1097/ICU.0000000000000129.
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[Sources of error in Goldmann applanation tonometry].[Goldmann压平眼压计测量中的误差来源]
Ophthalmologe. 2011 Jun;108(6):546-52. doi: 10.1007/s00347-011-2370-5.
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Botulinum toxin in the treatment of blepharospasm and hemifacial spasm.肉毒杆菌毒素治疗眼睑痉挛和半面痉挛。
J Neural Transm (Vienna). 2008;115(4):585-91. doi: 10.1007/s00702-007-0768-7. Epub 2007 Jun 11.
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Botulinum toxin in ophthalmology.眼科中的肉毒杆菌毒素。
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