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可卡因诱发的A型主动脉夹层延伸至双侧髂总动脉。

Cocaine-induced Type-A Aortic Dissection Extending to the Common Iliac Arteries.

作者信息

Mohamed Mohamed A, Abraham Rohit, Maraqa Tareq I, Elian Samir

机构信息

Michigan State University College of Human Medicine.

Trauma Department, Hurley Medical Center, Michigan State University College of Human Medicine.

出版信息

Cureus. 2018 Jan 12;10(1):e2059. doi: 10.7759/cureus.2059.

DOI:10.7759/cureus.2059
PMID:29545982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5849347/
Abstract

Aortic dissection is a rare and fatal complication of cocaine-induced hypertension. The injury mechanism is through shear stress that penetrates the intimal vessel layer, allowing blood flow to separate intimal and medial layers. Due to its scarcity and the paucity of related literature, our knowledge of this condition is limited. We present a rare case of a cocaine-induced aortic dissection, which extended continuously from the aortic root to the common iliacs, along with a literature review of similar cases. A 48-year-old male with recent cocaine use presented with left-sided chest-pain, which radiated to the back with nausea, diaphoresis, and shortness of breath. The patient was hypotensive. The initial radiographs and computed tomography were negative. The cardiac enzymes were elevated and the patient was admitted to rule out acute coronary syndrome. Next day echocardiogram and computed tomography revealed a Type-A aortic dissection continuously extending from the aortic root to the left common iliac artery. The patient was immediately transferred for surgery. Postoperatively, he developed acute kidney injury and shock liver. The patient status continued to deteriorate and he expired on postoperative day four. This case demonstrates the importance of prompt and thorough diagnostic evaluation, despite subjective history and initially negative imaging that might point towards other conditions. Unlike the previous cases, our case failed to identify the positive history of cocaine until nearly 24 hours into the patient's hospital course, suggesting a need for close monitoring in these patients and a possible need for repeat imaging.​​​​​​​.

摘要

主动脉夹层是可卡因诱发的高血压罕见且致命的并发症。损伤机制是通过穿透血管内膜层的剪切应力,使血流分离内膜层和中膜层。由于其罕见性以及相关文献的匮乏,我们对这种病症的了解有限。我们报告一例罕见的可卡因诱发的主动脉夹层病例,该夹层从主动脉根部持续延伸至双侧髂总动脉,并对类似病例进行文献综述。一名近期使用过可卡因的48岁男性,出现左侧胸痛,疼痛放射至背部,并伴有恶心、多汗和呼吸急促。患者血压降低。最初的X线片和计算机断层扫描结果均为阴性。心肌酶升高,患者入院以排除急性冠状动脉综合征。次日,超声心动图和计算机断层扫描显示为A型主动脉夹层,从主动脉根部持续延伸至左髂总动脉。患者立即被转至外科手术。术后,他出现急性肾损伤和休克肝。患者病情持续恶化,术后第四天死亡。该病例表明,尽管主观病史和最初的影像学检查结果为阴性(可能提示其他病症),但及时、全面的诊断评估仍很重要。与之前的病例不同,我们的病例直到患者住院近24小时才发现可卡因使用的阳性病史,这表明对这些患者需要密切监测,可能还需要重复进行影像学检查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea91/5849347/3370182f647e/cureus-0010-00000002059-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea91/5849347/acdc94a20e0a/cureus-0010-00000002059-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea91/5849347/7162f4d13f0a/cureus-0010-00000002059-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea91/5849347/f5c812762c5e/cureus-0010-00000002059-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea91/5849347/d2bc643e9055/cureus-0010-00000002059-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea91/5849347/3370182f647e/cureus-0010-00000002059-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea91/5849347/acdc94a20e0a/cureus-0010-00000002059-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea91/5849347/7162f4d13f0a/cureus-0010-00000002059-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea91/5849347/f5c812762c5e/cureus-0010-00000002059-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea91/5849347/d2bc643e9055/cureus-0010-00000002059-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea91/5849347/3370182f647e/cureus-0010-00000002059-i05.jpg

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