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牛磺酸口服剂量和补充时间对人体耐力运动表现的影响:一项荟萃分析。

The Effects of an Oral Taurine Dose and Supplementation Period on Endurance Exercise Performance in Humans: A Meta-Analysis.

机构信息

School of Health, Sport and Applied Sciences, St Mary's University, London, TW1 4SX, UK.

School of Science and Technology, University of New England, Armidale, NSW, 2350, Australia.

出版信息

Sports Med. 2018 May;48(5):1247-1253. doi: 10.1007/s40279-018-0896-2.

DOI:10.1007/s40279-018-0896-2
PMID:29546641
Abstract

BACKGROUND

Taurine is central to many physiological processes, some of which are augmented by exogenous supply and have the potential to facilitate endurance performance; however, its independent effects on performance have not been systematically analysed.

OBJECTIVE

To evaluate the effects of isolated oral taurine ingestion on endurance performance and to assess the contribution of (1) the dose and (2) the supplementation period to the ergogenic effect.

METHODS

A search was performed using various databases in September 2017. The studies were screened using search criteria for eligibility. Ten peer-reviewed articles were identified for inclusion. A sub-analysis of time-to-exhaustion (TTE) trials (n = 7) was also performed. The effects of (1) dose and (2) the acute (single dose) or chronic (> 1 day) supplementation periods were assessed using meta-regression. The doses of taurine ranged from 1 to 6 g/day and were provided in single doses and for up to 2 weeks among a range of subjects.

RESULTS

Taurine ingestion improved overall endurance performance (Hedges' g = 0.40, 95% CI 0.12-0.67, P = 0.004), which was similar in TTE trials (Hedges' g = 0.43, 95% CI 0.12-0.75, P = 0.007). There were no differences between acute or chronic supplementation for the full sample (P = 0.897) or the TTE group (P = 0.896). The dose of taurine did not moderate its effect on endurance performance (P > 0.05).

CONCLUSION

Human endurance performance can be improved by orally ingesting a single dose of taurine in varying amounts (1-6 g).

摘要

背景

牛磺酸在许多生理过程中起着核心作用,其中一些过程通过外源性供应得到增强,并有潜力促进耐力表现;然而,其对表现的独立影响尚未得到系统分析。

目的

评估单独口服牛磺酸摄入对耐力表现的影响,并评估(1)剂量和(2)补充期对促进作用的贡献。

方法

2017 年 9 月,使用各种数据库进行了搜索。使用搜索标准筛选研究以确定其是否符合入选标准。确定了 10 篇同行评审的文章供纳入。还对力竭时间(TTE)试验(n = 7)进行了亚分析。使用荟萃回归评估(1)剂量和(2)急性(单次剂量)或慢性(> 1 天)补充期的影响。牛磺酸的剂量范围为 1 至 6 g/天,在各种受试者中单次给予剂量并持续 1 至 2 周。

结果

牛磺酸摄入可改善整体耐力表现(Hedges' g = 0.40,95%CI 0.12-0.67,P = 0.004),在 TTE 试验中也有相似的效果(Hedges' g = 0.43,95%CI 0.12-0.75,P = 0.007)。在整个样本(P = 0.897)或 TTE 组(P = 0.896)中,急性或慢性补充之间均无差异。牛磺酸的剂量并未调节其对耐力表现的影响(P > 0.05)。

结论

通过口服摄入不同剂量(1-6 g)的牛磺酸,可提高人体耐力表现。

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