Sokoya Mofiyinfolu, Gonzalez Joseph R, Winkler Andrew A
Department of Otolaryngology, University of Colorado School of Medicine, USA.
Department of Otolaryngology, University of Colorado School of Medicine, USA.
Am J Otolaryngol. 2018 May-Jun;39(3):303-306. doi: 10.1016/j.amjoto.2018.03.014. Epub 2018 Mar 5.
To evaluate whether a diagnosis of allergic rhinitis affects surgical outcomes of open septorhinoplasty (OSR) and to examine whether OSR provides the same level of improvement in quality of life to patients with and without allergic rhinitis.
STUDY DESIGN, SETTING, SUBJECTS AND METHODS: We performed a retrospective evaluation of 646 patients who underwent open septorhinoplasty in a tertiary otolaryngology practice between 2008 and 2015. Preoperative and postoperative quality of life (QoL) measurement using the validated Nasal Obstruction Symptom Evaluation (NOSE) Scale was performed on 307 patients meeting inclusion criteria. These patients were then divided into two groups based on a diagnosis of allergic rhinitis (non-AR vs AR). Comparisons were then made based on quality of life improvements by the NOSE score.
There were 213 patients in the non-AR group vs. 94 patients in the AR group. After OSR, patients in both groups experienced significant improvement in nasal airway obstruction. Pre-op NOSE score averages were similar for the non-AR and AR groups (69.9 vs 73.4 p = 0.087). Average improvement in NOSE score for the non-AR and AR groups at 30 days was 48.6 vs 45.9 (p = 0.41); and at 90 day of 48.1 vs 51.5 (p = 0.402).
Patients with and without allergic rhinitis experience similar OSR outcomes as measured by the NOSE score. Open septorhinoplasty addresses multiple components contributing to nasal airway obstruction, and may offset the effects of allergic rhinitis. When indicated, it should be offered to patients with allergic rhinitis after complete medical management.
评估变应性鼻炎的诊断是否会影响开放式鼻中隔鼻成形术(OSR)的手术效果,并研究OSR对有和没有变应性鼻炎的患者在生活质量改善方面是否提供相同水平的提升。
研究设计、地点、对象与方法:我们对2008年至2015年间在一家三级耳鼻喉科诊所接受开放式鼻中隔鼻成形术的646例患者进行了回顾性评估。对符合纳入标准的307例患者,使用经过验证的鼻阻塞症状评估(NOSE)量表进行术前和术后生活质量(QoL)测量。然后根据变应性鼻炎的诊断将这些患者分为两组(非变应性鼻炎组与变应性鼻炎组)。接着根据NOSE评分的生活质量改善情况进行比较。
非变应性鼻炎组有213例患者,变应性鼻炎组有94例患者。OSR术后,两组患者的鼻气道阻塞均有显著改善。非变应性鼻炎组和变应性鼻炎组术前NOSE评分平均值相似(69.9对73.4,p = 0.087)。非变应性鼻炎组和变应性鼻炎组在30天时NOSE评分的平均改善值分别为48.6和45.9(p = 0.41);在90天时分别为48.1和51.5(p = 0.402)。
通过NOSE评分衡量,有和没有变应性鼻炎的患者在OSR手术效果方面相似。开放式鼻中隔鼻成形术可解决导致鼻气道阻塞的多个因素,并且可能抵消变应性鼻炎的影响。如有指征,在完成药物治疗后应将其提供给变应性鼻炎患者。