Division of Pulmonary, Allergy and Critical Care Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
Division of Cardiothoracic Surgery, University of Wisconsin School of Medicine, Madison, Wisconsin.
J Heart Lung Transplant. 2018 May;37(5):548-563. doi: 10.1016/j.healun.2018.01.1309. Epub 2018 Feb 7.
Airway complications remain a major cause of morbidity and mortality after cardiothoracic transplantation. The reported incidence of airway ischemic complications varies widely, contributed to by the lack of a universally accepted grading system and standardized definitions. Furthermore, the majority of the existing classification systems fail to integrate the wide range of possible bronchial complications that may develop after lung transplant. Hence, a Working Group was created by the International Society for Heart and Lung Transplantation with the aim of elaborating a universal definition of adult and pediatric airway complications and grading system. One such area of focus is to understand the problem in the context of a more standardized consensus of classifying airway ischemia. This consensus definition will have major clinical, therapeutics, and research implications.
气道并发症仍然是心胸器官移植术后发病率和死亡率的主要原因。气道缺血性并发症的报告发生率差异很大，这是由于缺乏普遍接受的分级系统和标准化定义所致。此外，现有的大多数分类系统未能整合可能在肺移植后发生的广泛的支气管并发症。因此，国际心肺移植学会成立了一个工作组，旨在详细制定成人和儿科气道并发症和分级系统的通用定义。其中一个重点领域是在更标准化的气道缺血分类共识的背景下理解这一问题。这一共识定义将具有重大的临床、治疗和研究意义。
