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蒙特利尔认知评估量表(MoCA)及其记忆任务在检测轻度认知障碍中的作用。

The role of the Montreal Cognitive Assessment (MoCA) and its memory tasks for detecting mild cognitive impairment.

机构信息

Department of Neurology, China-Japan Friendship Hospital, Yinghua East Road, Chaoyang District, Beijing, 100029, China.

Department of Senior Official Ward, China-Japan Friendship Hospital, Beijing, 100029, China.

出版信息

Neurol Sci. 2018 Jun;39(6):1029-1034. doi: 10.1007/s10072-018-3319-0. Epub 2018 Mar 17.

Abstract

To investigate the role of the Montreal Cognitive Assessment (MoCA) (Beijing version) and its memory tasks on detecting different mild cognitive impairment (MCI) subtypes including amnestic MCI (aMCI) and nonamnestic MCI (naMCI) in memory clinics. A total of 121 patients with MCI and 53 healthy controls were included. Fifty-six aMCI-multiple domains (amMCI), 32 aMCI-single domain (asMCI), and 33 naMCI patients were diagnosed according to extensive cognitive tests. All participants were administered by the Mini Mental State Examination (MMSE) and the MoCA. Patients with amMCI performed worse than patients with asMCI, naMCI, and healthy controls on the MMSE and the MoCA (p < 0.001). The area under the curve (AUC) value for the MoCA when comparing the amMCI and control groups was 0.884 (p < 0.001), which was superior to that of the MMSE. The AUC value decreased to 0.687 when applied to the naMCI and control groups (p = 0.007), which was still higher than that of the Rey Auditory Verbal Learning Test (RAVLT) or the Rey-Osterrieth complex figure (ROCF). Delayed free recall or category prompted recall in the MoCA had roles in differentiating asMCI and controls groups with AUC value of 0.717 (p = 0.002) and 0.691 (p = 0.005), respectively. The MoCA is a good screening tool for detecting different types of MCI and is suitable for patients in outpatient clinics.

摘要

目的

探讨蒙特利尔认知评估(MoCA)(北京版)及其记忆任务在记忆门诊中检测不同类型轻度认知障碍(MCI)的作用,包括遗忘型 MCI(aMCI)和非遗忘型 MCI(naMCI)。共纳入 121 例 MCI 患者和 53 例健康对照者。根据广泛的认知测试,诊断 56 例多领域遗忘型 MCI(amMCI)、32 例单领域遗忘型 MCI(asMCI)和 33 例非遗忘型 MCI 患者。所有参与者均接受简易精神状态检查(MMSE)和 MoCA 测试。amMCI 患者在 MMSE 和 MoCA 上的表现均差于 asMCI、naMCI 和健康对照组(p<0.001)。MoCA 用于比较 amMCI 组和对照组时的曲线下面积(AUC)值为 0.884(p<0.001),优于 MMSE。当应用于 naMCI 组和对照组时,AUC 值降至 0.687(p=0.007),仍高于 Rey 听觉言语学习测验(RAVLT)或 Rey-Osterrieth 复杂图形(ROCF)。MoCA 中的延迟自由回忆或类别提示回忆在区分 asMCI 和对照组方面具有作用,AUC 值分别为 0.717(p=0.002)和 0.691(p=0.005)。MoCA 是一种检测不同类型 MCI 的良好筛查工具,适用于门诊患者。

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