Quentin R, Goudeau A, Burfin E, Pinon G, Berger C, Laugier J, Soutoul J H
Presse Med. 1987 Jun 20;16(24):1181-4.
In a systematic screening programme for neonatal infections involving 16,008 births, Haemophilus influenzae was isolated in 14 mother-infant couples (0.8 to 1,000 births). Comparisons with other series published in the U.S.A. showed similar circumstances of occurrence and initial clinical manifestations. However, the course of the infection was different, since there was no septicaemia or meningitis in our series. This raises the question of whether the strains responsible for the disease in the U.S.A. have a particular aggressiveness that is unidentifiable by serotype or biotype. In view of the post-partum occurrence of pelvic infections after isolation of H. influenzae during high risk deliveries, asymptomatic parturient women should be treated prophylactically. The 14 strains of H. influenzae isolated, most of them non capsulated and 2/3 of them of biotype IV, probably were of genital origin, although there was no evidence of cervico-vaginal infection. These results are consistent with the concept of genitotropic H. influenzae.
在一项针对16008例分娩的新生儿感染系统筛查计划中,在14对母婴中分离出了流感嗜血杆菌(每1000例分娩中有0.8例)。与美国发表的其他系列研究进行比较,发现发病情况和初始临床表现相似。然而,感染过程有所不同,因为在我们的系列研究中没有败血症或脑膜炎病例。这就提出了一个问题,即在美国导致该疾病的菌株是否具有一种无法通过血清型或生物型识别的特殊侵袭性。鉴于在高危分娩期间分离出流感嗜血杆菌后发生产后盆腔感染,无症状产妇应进行预防性治疗。分离出的14株流感嗜血杆菌,大多数无荚膜,其中2/3为生物型IV,尽管没有宫颈阴道感染的证据,但可能起源于生殖道。这些结果与嗜性流感嗜血杆菌的概念一致。