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五种新型喹诺酮类药物对88株生殖道和新生儿嗜血杆菌分离株的体外活性

In vitro activities of five new quinolones against 88 genital and neonatal Haemophilus isolates.

作者信息

Quentin R, Koubaa N, Cattier B, Gavignet M, Goudeau A

机构信息

Laboratoires de Bactériologie et Virologie, Centre Hospitalier Régional et Universitaire, Bretonneau, Tours, France.

出版信息

Antimicrob Agents Chemother. 1988 Jan;32(1):147-9. doi: 10.1128/AAC.32.1.147.

Abstract

In vitro activities of five new quinolones against 88 strains of Haemophilus influenzae and H. parainfluenzae isolated from genitourinary or neonatal infections were studied. All strains were susceptible, and MICs were similar to those for respiratory tract isolates. However, H. influenzae biotype IV appeared to be more susceptible to norfloxacin, enoxacin, and ciprofloxacin than the other biotypes were.

摘要

研究了五种新型喹诺酮类药物对从泌尿生殖道或新生儿感染中分离出的88株流感嗜血杆菌和副流感嗜血杆菌的体外活性。所有菌株均敏感,其最低抑菌浓度(MIC)与呼吸道分离株相似。然而,IV型流感嗜血杆菌似乎比其他生物型对诺氟沙星、依诺沙星和环丙沙星更敏感。

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