Von Theobald P, Roffé J L, Berrocal J, Le Porrier M, Lévy G, Muller G
Presse Med. 1987 Jun 27;16(25):1239-41.
Treatment of subdiaphragmatic Hodgkin's diseases with combined radio- and chemotherapy results in castration of more than 80% of the women treated, despite oophoropexy. We suggest a new technique of subcutaneous ovarian grafting which provides full protection against irradiation and preserves both ovarian function and fertility. To be successful this technique requires the creation, prior to grafting, of a receptive cavity, two surgical teams working together, and the use of an operative microscope during transplantation. A mature oocyte was collected by puncture of the ovary-containing cavity one year after the operation.
尽管进行了卵巢固定术,但采用放疗和化疗联合治疗膈下霍奇金病会导致超过80%接受治疗的女性出现卵巢功能丧失。我们提出一种新的皮下卵巢移植技术,该技术可提供全面的辐射防护,并保留卵巢功能和生育能力。要使该技术成功,需要在移植前创建一个容纳腔,两个手术团队协同工作,并在移植过程中使用手术显微镜。术后一年通过穿刺含卵巢腔收集到了成熟卵母细胞。