Leporrier M, von Theobald P, Roffe J L, Muller G
Département d'Hématologie Clinique, Centre Hospitalier Universitaire, Caen France.
Cancer. 1987 Nov 1;60(9):2201-4. doi: 10.1002/1097-0142(19871101)60:9<2201::aid-cncr2820600915>3.0.co;2-z.
The authors describe a new technique for the subcutaneous heterotopic transplantation of the ovary before pelvic irradiation to treat Hodgkin's disease. Creation of a cavity to receive the transplant and the use of two surgical teams and the surgical microscope during the operation ensured its successful outcome. The transplanted ovary was followed up clinically and by ultrasound monitoring: ovarian cycles remained regular despite radiotherapy, and follicle growth occurred normally. In comparison to other types of oophoropexy described in the literature, the advantages of this technique included total protection of the ovary from irradiation, and conservation of ovarian function and fertility. One year after the procedure, puncture of the ovarian compartment produced a mature oocyte specimen.
作者描述了一种在盆腔放疗前进行卵巢皮下异位移植以治疗霍奇金病的新技术。术中创建一个容纳移植卵巢的腔隙,并使用两个手术团队和手术显微镜确保了手术的成功。对移植的卵巢进行了临床随访和超声监测:尽管进行了放疗,卵巢周期仍保持规律,卵泡正常生长。与文献中描述的其他类型的卵巢固定术相比,该技术的优点包括卵巢完全免受辐射,以及保留卵巢功能和生育能力。术后一年,对卵巢腔进行穿刺获得了成熟的卵母细胞标本。