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一种在盆腔放疗前保护卵巢功能的新技术。异位卵巢自体移植。

A new technique to protect ovarian function before pelvic irradiation. Heterotopic ovarian autotransplantation.

作者信息

Leporrier M, von Theobald P, Roffe J L, Muller G

机构信息

Département d'Hématologie Clinique, Centre Hospitalier Universitaire, Caen France.

出版信息

Cancer. 1987 Nov 1;60(9):2201-4. doi: 10.1002/1097-0142(19871101)60:9<2201::aid-cncr2820600915>3.0.co;2-z.

DOI:10.1002/1097-0142(19871101)60:9<2201::aid-cncr2820600915>3.0.co;2-z
PMID:3440230
Abstract

The authors describe a new technique for the subcutaneous heterotopic transplantation of the ovary before pelvic irradiation to treat Hodgkin's disease. Creation of a cavity to receive the transplant and the use of two surgical teams and the surgical microscope during the operation ensured its successful outcome. The transplanted ovary was followed up clinically and by ultrasound monitoring: ovarian cycles remained regular despite radiotherapy, and follicle growth occurred normally. In comparison to other types of oophoropexy described in the literature, the advantages of this technique included total protection of the ovary from irradiation, and conservation of ovarian function and fertility. One year after the procedure, puncture of the ovarian compartment produced a mature oocyte specimen.

摘要

作者描述了一种在盆腔放疗前进行卵巢皮下异位移植以治疗霍奇金病的新技术。术中创建一个容纳移植卵巢的腔隙,并使用两个手术团队和手术显微镜确保了手术的成功。对移植的卵巢进行了临床随访和超声监测:尽管进行了放疗,卵巢周期仍保持规律,卵泡正常生长。与文献中描述的其他类型的卵巢固定术相比,该技术的优点包括卵巢完全免受辐射,以及保留卵巢功能和生育能力。术后一年,对卵巢腔进行穿刺获得了成熟的卵母细胞标本。

相似文献

1
A new technique to protect ovarian function before pelvic irradiation. Heterotopic ovarian autotransplantation.一种在盆腔放疗前保护卵巢功能的新技术。异位卵巢自体移植。
Cancer. 1987 Nov 1;60(9):2201-4. doi: 10.1002/1097-0142(19871101)60:9<2201::aid-cncr2820600915>3.0.co;2-z.
2
[First heterotopic ovarian autotransplantation in the female].
J Gynecol Obstet Biol Reprod (Paris). 1988;17(1):97-102.
3
[Heterotopic autotransplantation of the ovary in women].[女性卵巢异位自体移植]
Presse Med. 1987 Jun 27;16(25):1239-41.
4
Successful human ovarian autotransplantation to the upper arm.人类卵巢成功自体移植至上臂。
Cancer. 2004 Dec 15;101(12):2771-8. doi: 10.1002/cncr.20715.
5
Preservation of ovarian function in pelvic radiation for Hodgkin's disease.
Arch Surg. 1970 Mar;100(3):236-7. doi: 10.1001/archsurg.1970.01340210012004.
6
Reproductive and endocrine function in patients with Hodgkin's disease: effects of oophoropexy and irradiation.霍奇金病患者的生殖与内分泌功能:卵巢固定术及放疗的影响
Br J Cancer. 1976 Feb;33(2):226-31. doi: 10.1038/bjc.1976.29.
7
Prolonged amenorrhea associated with total nodal irradiation for Hodgkin's disease.霍奇金病全淋巴结照射所致的长期闭经。
J Natl Med Assoc. 1996 Jun;88(6):391-3.
8
Preservation of ovarian function in patients requiring radiotherapy for para-aortic and pelvic Hodgkin's disease.
Lancet. 1972 Jun 17;1(7764):1307-8. doi: 10.1016/s0140-6736(72)91035-5.
9
Pregnancy following oophoropexy and total nodal irradiation in women with Hodgkin's disease.霍奇金病女性患者卵巢固定术和全淋巴结照射后的妊娠情况。
Cancer. 1976 Dec;38(6):2263-8. doi: 10.1002/1097-0142(197612)38:6<2263::aid-cncr2820380612>3.0.co;2-s.
10
[Preservation of ovarian function in 2 young women with Hodgkin disease by laparoscopic transposition of the ovaries prior to abdominal irradiation].[通过腹腔镜将卵巢移位至腹部放疗前,对两名年轻霍奇金病女性患者卵巢功能的保护]
Ned Tijdschr Geneeskd. 1999 Feb 6;143(6):308-12.

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Clin Med Insights Reprod Health. 2019 Dec 3;13:1179558119884945. doi: 10.1177/1179558119884945. eCollection 2019.
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J Reprod Infertil. 2018 Jul-Sep;19(3):125-132.
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Successful fertility following optimized perfusion and cryopreservation of whole ovary and allotransplantation in a premature ovarian insufficiency rat model.成功实现优化灌注和冷冻保存整个卵巢并同种异体移植,改善了卵巢早衰大鼠模型的生育能力。
J Ovarian Res. 2018 May 2;11(1):35. doi: 10.1186/s13048-018-0401-4.
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