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卵巢固定术与霍奇金病的治疗。对风险和益处的重新评估。

Oophoropexy and the management of Hodgkin's disease. A reevaluation of the risks and benefits.

作者信息

Gabriel D A, Bernard S A, Lambert J, Croom R D

出版信息

Arch Surg. 1986 Sep;121(9):1083-5. doi: 10.1001/archsurg.1986.01400090115021.

Abstract

Female patients with Hodgkin's disease who undergo staging laparotomy frequently have oophoropexy performed to preserve both fertility and hormone production. Because of recent changes in therapy favoring systemic chemotherapy rather than total nodal irradiation for patients with stage III Hodgkin's disease, the need for oophoropexy may be less than previously described. Thirty-nine women of childbearing age underwent laparotomy at the University of North Carolina, Chapel Hill, from 1970 to 1984. Twenty-seven patients underwent oophoropexy. Only three of these patients would have needed this procedure based on their subsequent therapy. Two patients required additional gynecologic surgery because of complications related to the oophoropexy. The success rate in preservation of menstrual function and fertility is also discussed. We review the previous experience with oophoropexy and suggest an alternative approach to the routine use of this procedure.

摘要

接受分期剖腹术的霍奇金病女性患者经常进行卵巢固定术,以保留生育能力和激素分泌。由于近期治疗方式的改变,对于Ⅲ期霍奇金病患者,全身化疗而非全淋巴结照射更为常用,卵巢固定术的必要性可能比之前描述的要小。1970年至1984年期间,39名育龄女性在北卡罗来纳大学教堂山分校接受了剖腹术。27名患者接受了卵巢固定术。根据后续治疗情况,这些患者中只有3名需要进行该手术。2名患者因卵巢固定术相关并发症需要额外的妇科手术。还讨论了保留月经功能和生育能力的成功率。我们回顾了之前卵巢固定术的经验,并建议对该手术的常规使用采取另一种方法。

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