Sato S, Ohnishi K, Sugita S, Okuda K
Radiology. 1987 Aug;164(2):347-52. doi: 10.1148/radiology.164.2.2955448.
The accuracy of the duplex Doppler ultrasound system in the measurement of blood flow in the splenic artery and the superior mesenteric artery was evaluated in seven anesthetized dogs by comparing blood flow recordings obtained simultaneously with the electromagnetic flowmeter, with those obtained with the combination of B-mode and M-mode scanning. Various flow rates were produced by the infusion of dopamine. Splenic artery blood flow and superior mesenteric artery blood flow measured with the duplex system exhibited significant correlations with corresponding values obtained with electromagnetic flow measurements (r = .93 and r = .93, respectively). Changes in splanchnic circulation with the progression of chronic liver disease in humans were then investigated with the use of the duplex system. Splenic artery blood flow and superior mesenteric artery blood flow were significantly increased in patients with cirrhosis compared with patients with chronic hepatitis and healthy subjects. These results indicate that a hyperdynamic circulatory state may develop in the splanchnic circulation of the intestine and spleen in cirrhotic patients.
通过将双功多普勒超声系统与电磁流量计同时获得的血流记录，与B模式和M模式扫描相结合获得的血流记录进行比较，在7只麻醉犬中评估了双功多普勒超声系统测量脾动脉和肠系膜上动脉血流的准确性。通过输注多巴胺产生不同的流速。用双功系统测量的脾动脉血流和肠系膜上动脉血流与电磁流量测量获得的相应值显示出显著相关性（分别为r = 0.93和r = 0.93）。然后使用双功系统研究了人类慢性肝病进展过程中内脏循环的变化。与慢性肝炎患者和健康受试者相比，肝硬化患者的脾动脉血流和肠系膜上动脉血流显著增加。这些结果表明，肝硬化患者的肠和脾的内脏循环可能会出现高动力循环状态。
