Mattingly Anne E, Weaver Abigail A, Dimkovikj Aleksandar, Shrout Joshua D
Department of Civil and Environmental Engineering and Earth Sciences, University of Notre Dame.
Department of Biological Sciences, University of Notre Dame.
J Bacteriol. 2018 Mar 19;200(11):e00014-18. doi: 10.1128/JB.00014-18.
The degree to which surface motile bacteria explore their surroundings is influenced by aspects of their local environment. Accordingly, regulation of surface motility is controlled by numerous chemical, physical, and biological stimuli. Discernment of such regulation due to these multiple cues is a formidable challenge. Additionally inherent ambiguity and variability from the assays used to assess surface motility can be an obstacle to clear delineation of regulated surface motility behavior. Numerous studies have reported single environmental determinants of microbial motility and lifestyle behavior but the translation of these data to understand surface motility and bacterial colonization of human host or environmental surfaces is unclear. Here, we describe the current state of the field and our understanding of exogenous factors that influence bacterial surface motility.
表面运动性细菌探索其周围环境的程度受到其局部环境各方面因素的影响。因此，表面运动性的调节受多种化学、物理和生物刺激的控制。辨别由这些多种线索导致的这种调节是一项艰巨的挑战。此外，用于评估表面运动性的测定方法所固有的模糊性和变异性可能成为清晰描绘受调节的表面运动性行为的障碍。许多研究报告了微生物运动性和生活方式行为的单一环境决定因素，但这些数据对于理解人类宿主或环境表面的表面运动性和细菌定殖的转化尚不清楚。在此，我们描述了该领域的现状以及我们对影响细菌表面运动性的外源性因素的理解。
