感染复发：一例化疗后肺孢子丝菌病复发病例
The Infection Returns: A Case of Pulmonary Sporotrichosis Relapse after Chemotherapy.
作者信息
Farooqui Samid M, Youness Houssein
机构信息
Department of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Section of Pulmonary, Critical Care, and Sleep Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
出版信息
Case Rep Med. 2018 Feb 18;2018:1384029. doi: 10.1155/2018/1384029. eCollection 2018.
BACKGROUND
Pulmonary sporotrichosis is a rare disease caused by a dimorphic fungus, . It is rarely found in association with malignancy. We present a case of pulmonary sporotrichosis recurrence after chemotherapy.
CASE PRESENTATION
A 44-year-old man, treated for pulmonary sporotrichosis in the past, presented with dysphagia and was found to have squamous cell carcinoma of the esophagus. After undergoing chemotherapy, extensive cavitary lesions were observed on thoracic computed tomography scan. A bronchoalveolar lavage revealed the presence of . Despite treatment with itraconazole, he eventually required a left pneumonectomy for progressive destructive cavitary lesions involving the left lung.
CONCLUSION
This case highlights the importance of considering past fungal infections, albeit cured, in patients initiating immunosuppressive therapy.
背景
肺孢子丝菌病是一种由双相真菌引起的罕见疾病。它很少与恶性肿瘤相关。我们报告一例化疗后肺孢子丝菌病复发的病例。
病例介绍
一名44岁男性，既往曾接受肺孢子丝菌病治疗，现出现吞咽困难，经检查发现患有食管鳞状细胞癌。化疗后，胸部计算机断层扫描显示广泛的空洞性病变。支气管肺泡灌洗发现存在……。尽管接受了伊曲康唑治疗，但由于左肺出现进行性破坏性空洞性病变，他最终需要进行左肺切除术。
结论
该病例强调了在开始免疫抑制治疗的患者中考虑既往真菌感染（尽管已治愈）的重要性。
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