Suppr超能文献

孤立性单关节炎

Isolated Monoarthritis.

作者信息

Barbaryan Aram, El Atrouni Wissam, Bailuc Stefania, Jones Matthew W, Bhakta Maharshi, Mahmoud Khaldoun Haj, Mirrakhimov Aibek E

机构信息

Department of Internal Medicine, Division of General, Geriatric & Hospital Medicine, University of Kansas Health System, Kansas City, KS, USA.

Division of Infectious Diseases, Department of Internal Medicine, University of Kansas Health System, Kansas City, KS, USA.

出版信息

Case Rep Infect Dis. 2018 Jun 12;2018:9037657. doi: 10.1155/2018/9037657. eCollection 2018.

Abstract

is a rare cause of arthritis. Its course is indolent with lack of constitutional symptoms resulting in delayed presentation and diagnosis. It is a dimorphic fungus found ubiquitously in sphagnum moss, decaying vegetation, soil, and hay. Inoculation of dirt into the skin and soft tissues and, in rare instances, inhalation of aerosolized conidia from soil and plants can lead to infection. Subacute and chronic involvement of skin and subcutaneous tissues is the most common manifestation of sporotrichosis in immunocompetent hosts. In patients with underlying risk factors (HIV, alcoholism, diabetes mellitus, organ transplant patients, immunosuppressive medications, steroids, and malignancies), it can often have disseminated visceral, osteoarticular, meningeal, and pulmonary involvement. Sporothrical arthritis most commonly infects knee joint followed by hand and wrist joints. A culture of is the gold standard for the diagnosis of sporotrichosis. Itraconazole is the drug of choice for osteoarticular sporotrichosis. We present a case of sporotrichal arthritis in a patient without skin or lymph node involvement who underwent treatment with itraconazole resulting in resolution of his symptoms.

摘要

是关节炎的罕见病因。其病程进展缓慢,无全身症状,导致就诊和诊断延迟。它是一种双相真菌,广泛存在于泥炭藓、腐烂植被、土壤和干草中。污垢接种到皮肤和软组织,在极少数情况下,吸入来自土壤和植物的气溶胶化分生孢子可导致感染。皮肤和皮下组织的亚急性和慢性受累是免疫功能正常宿主孢子丝菌病最常见的表现。在有潜在危险因素的患者(艾滋病毒、酗酒、糖尿病、器官移植患者、免疫抑制药物、类固醇和恶性肿瘤)中,它常可出现播散性内脏、骨关节、脑膜和肺部受累。孢子丝菌性关节炎最常感染膝关节,其次是手和腕关节。培养是孢子丝菌病诊断的金标准。伊曲康唑是骨关节孢子丝菌病的首选药物。我们报告一例无皮肤或淋巴结受累的孢子丝菌性关节炎患者,接受伊曲康唑治疗后症状缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a1c/6020502/e8282d1a0e4e/CRIID2018-9037657.001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验