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沙特阿拉伯北部阿拉尔地区的母胎恒河猴(Rh)因子不相容性。

Maternal-fetal Rhesus (Rh) factor incompatibility in Arar, northern Saudi Arabia.

作者信息

Aljuhaysh Raghad Mubarak, El-Fetoh Nagah Mohamed Abo, Alanazi Malak Ibrahim, Albaqawi Afaf Shuaib, Alanazi Wafa Mohammed, Alanazi Najah Salah, Alanazi Reham Muqbil, Alanazi Atheer Mutab, Alnemer Eiman Mohammad, Alenezi Rahma Abdulhadi, Alabdullatif Tasleem Khoudier, Alanazi Rehab Abdallah, Alanazi Samiyah Sarhan, Alsultan Kawthar Saeed, Alanazi Ibtisam Matan, Alsunayni Duaa Sami

机构信息

Intern, Faculty of Medicine, Northern Border University, Arar, Kingdom of Saudi Arabia.

Associate Professor of Public Health and Community Medicine, Faculty of Medicine, Northern Border University, Arar, Kingdom of Saudi Arabia.

出版信息

Electron Physician. 2017 Dec 25;9(12):5908-5913. doi: 10.19082/5908. eCollection 2017 Dec.

Abstract

BACKGROUND AND AIM

Rh isoimmunization still contributes to the neonatal morbidity and mortality due to non-immunization, under-immunization, and in rare cases, false Rh typing. The main objective of this study was to determine the prevalence of Rh incompatibility, mothers' knowledge about Rh incompatibility, mothers' knowledge about anti-D immunoglobulin and to show the pregnancy outcome of Rh negative mothers.

METHODS

A cross-sectional study was carried out at the Maternity and Children Hospital in Arar city from November 2016 to May 2017. All pregnant mothers attending the Maternity and Children Hospital for pregnancy follow up or delivery, during the study period were studied. Data were collected by means of personal interview with the sampled population using a researcher-made questionnaire covering the needed data. Data were analyzed by SPSS version 16, using descriptive statistics and Chi-Square test.

RESULTS

Of the studied mothers, 23% were Rh negative. Only 38% of the studied mothers had knowledge about Rh incompatibility, 68.5% had knowledge about anti-D and 51% had knowledge about time of administration of anti D. Considering pregnancy outcome; 55% of the delivered babies needed incubation after delivery, 23.3% of those babies were born to Rh negative mothers. However, 6.7% of the incubated children died after incubation (47.8% of them belong to Rh negative mothers).

CONCLUSION

About a quarter of the mothers in the studied population were Rh negative. Mothers had a low level of knowledge about Rh incompatibility and anti-D immunoglobulin and its administration. Health education sittings are needed to increase public awareness about this important issue.

摘要

背景与目的

由于未免疫、免疫不足以及在罕见情况下的假Rh血型鉴定,Rh血型同种免疫仍然是新生儿发病和死亡的原因之一。本研究的主要目的是确定Rh血型不相容的患病率、母亲对Rh血型不相容的了解程度、母亲对抗D免疫球蛋白的了解程度,并展示Rh阴性母亲的妊娠结局。

方法

2016年11月至2017年5月在阿拉尔市妇幼医院进行了一项横断面研究。对研究期间到妇幼医院进行孕期随访或分娩的所有孕妇进行了研究。通过使用研究人员制作的涵盖所需数据的问卷对抽样人群进行个人访谈来收集数据。使用SPSS 16版软件进行数据分析,采用描述性统计和卡方检验。

结果

在研究的母亲中,23%为Rh阴性。只有38%的研究母亲了解Rh血型不相容,68.5%了解抗D,51%了解抗D的给药时间。考虑到妊娠结局;55%的分娩婴儿产后需要进行孵化,其中23.3%的婴儿母亲为Rh阴性。然而,6.7%的孵化儿童在孵化后死亡(其中47.8%属于Rh阴性母亲)。

结论

研究人群中约四分之一的母亲为Rh阴性。母亲对Rh血型不相容、抗D免疫球蛋白及其给药的了解程度较低。需要开展健康教育讲座,以提高公众对这一重要问题的认识。

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本文引用的文献

1
Occurrence of ABO And RhD Incompatibility with Rh Negative Mothers.Rh阴性母亲中ABO和RhD血型不相容的发生情况。
Mater Sociomed. 2013 Dec;25(4):255-8. doi: 10.5455/msm.2013.25.255-258. Epub 2013 Nov 24.

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