1996 - 2015年巴西及各地区按性别划分的结直肠癌死亡率演变情况
EVOLUTION OF MORTALITY FOR COLORECTAL CANCER IN BRAZIL AND REGIONS, BY SEX, 1996-2015.
作者信息
Dutra Viviane Gomes Parreira, Parreira Virgilio Augusto Gomes, Guimarães Raphael Mendonça
机构信息
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro, RJ, Brasil.
Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA), Rio de Janeiro, RJ, Brasil.
出版信息
Arq Gastroenterol. 2018 Jan-Mar;55(1):61-65. doi: 10.1590/S0004-2803.201800000-12.
BACKGROUND
Colorectal cancer is among the three most frequent neoplasms in Brazil, being a public health problem.
OBJECTIVE
To describe distribution pattern of colorectal cancer mortality in Brazil and regions, according to sex, between 1996 and 2015.
METHODS
Values of standardized and stratified mortality rates by sex between 1996 and 2015 were used, through polynomial regression models and joinpoint analysis.
RESULTS
It was observed that, for linear trends in mortality rates, for both sexes, there is a statistically significant trend increasing in both models, with rates and trends, and higher for men than for women, respectively, 7.3% per year (R2=0.95, P<0.001) and 6.5% per year (R2=0.87, P<0.001). It is observed a difference in magnitude and behavior of trend between the regions.
CONCLUSION
It is understood that it is important to know the trend of rates in order to define priority populations for early interventions that increase survival and reduce mortality.
背景
结直肠癌是巴西最常见的三种肿瘤之一，是一个公共卫生问题。
目的
描述1996年至2015年间巴西及各地区按性别划分的结直肠癌死亡率分布模式。
方法
通过多项式回归模型和连接点分析，使用1996年至2015年间按性别标准化和分层的死亡率值。
结果
观察到，对于死亡率的线性趋势，在两种模型中，男女两性的死亡率均有统计学意义的上升趋势，其速率和趋势分别为男性每年7.3%（R2 = 0.95，P < 0.001）和女性每年6.5%（R2 = 0.87，P < 0.001）。各地区之间在趋势的幅度和行为上存在差异。
结论
据了解，了解发病率趋势对于确定早期干预的优先人群非常重要，早期干预可提高生存率并降低死亡率。
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