Maxwell Lauren, Nandi Arijit, Benedetti Andrea, Devries Karen, Wagman Jennifer, García-Moreno Claudia
Epidemiology, Biostatistics, and Occupational Health, McGill University, Montréal, Quebec, Canada.
Institute for Health and Social Policy, McGill University, Montréal, Quebec, Canada.
BMJ Glob Health. 2018 Jan 13;3(1):e000304. doi: 10.1136/bmjgh-2017-000304. eCollection 2018.
Inadequately spaced pregnancies, defined as pregnancies fewer than 18 months apart, are linked to maternal, infant, and child morbidity and mortality, and adverse social, educational and economic outcomes in later life for women and children. Quantifying the relation between intimate partner violence (IPV) and women's ability to space and time their pregnancies is an important part of understanding the burden of disease related to IPV.
We applied Cox proportional hazards models to monthly data from the Demographic and Health Surveys' Reproductive Health Calendar to compare interpregnancy intervals for women who experienced physical, sexual and/or emotional IPV in 29 countries. We conducted a one-stage meta-analysis to identify the periods when women who experienced IPV were at the highest risk of unintended and incident pregnancy, and a two-stage meta-analysis to explore cross-country variations in the magnitude of the relation between women's experience of IPV and pregnancy spacing.
For the one-stage analysis, considering 52 959 incident pregnancies from 90 446 women, which represented 232 394 person-years at risk, women's experience of IPV was associated with a 51% increase in the risk of pregnancy (95% CI 1.38 to 1.66), although this association decreased over time. When limiting our inference to unintended pregnancies that resulted in live births, women's experience of IPV was associated with a 30% increase in the risk of unintended pregnancy (95% CI 1.25 to 1.34; n=13 541 pregnancies, 92 848 women, 310 319 person-years at risk). In the two-stage meta-analyses, women's experience of IPV was associated with a 13% increase in the probability of incident pregnancy (95% CI 1.07 to 1.20) and a 28% increase in the likelihood of unintended pregnancy (95% CI 1.19 to 1.38).
Across countries, women's experience of IPV is associated with a reduction in time between pregnancies and an increase in the risk of unintended pregnancy; the magnitude of this effect varied by country and over time.
间隔时间过短的妊娠(定义为两次妊娠间隔少于18个月)与孕产妇、婴儿及儿童的发病和死亡相关,并且会给妇女和儿童日后的社会、教育及经济状况带来不良影响。量化亲密伴侣暴力(IPV)与女性安排妊娠时间间隔能力之间的关系,是理解与IPV相关疾病负担的重要组成部分。
我们将Cox比例风险模型应用于人口与健康调查生殖健康日历中的月度数据,以比较29个国家中遭受身体、性和/或情感IPV的女性的妊娠间隔。我们进行了一项单阶段荟萃分析,以确定遭受IPV的女性意外妊娠和意外受孕风险最高的时期,并进行了两阶段荟萃分析,以探讨各国女性IPV经历与妊娠间隔关系大小的差异。
在单阶段分析中,考虑到来自90446名女性的52959次意外妊娠,代表232394人年的风险暴露,女性的IPV经历与妊娠风险增加51%相关(95%CI 1.38至1.66),尽管这种关联会随时间减弱。当我们将推断范围限制在导致活产的意外妊娠时,女性的IPV经历与意外妊娠风险增加30%相关(95%CI 1.25至1.34;n = 13541次妊娠,92848名女性,310319人年的风险暴露)。在两阶段荟萃分析中,女性的IPV经历与意外受孕概率增加13%(95%CI 1.07至1.20)和意外妊娠可能性增加28%(95%CI 1.19至1.38)相关。
在各个国家,女性的IPV经历与妊娠间隔时间缩短以及意外妊娠风险增加相关;这种影响的大小因国家和时间而异。