Moon Jeong Jae, Park Sam-Guk, Ryu Seung Min, Park Chan-Ho
Department of Orthopedic Surgery, Yeungnam University Medical Center, Daegu, Korea.
J Bone Metab. 2018 Feb;25(1):15-21. doi: 10.11005/jbm.2018.25.1.15. Epub 2018 Feb 28.
We sought to develop a novel index based on the skeletal muscle mass that reflects the change of quality of life (QOL), and is the most appropriate index for the body composition of the elderly in Korea. Whether lower extremity skeletal muscle mass index (LESMI) is an appropriate novel new index to diagnose patients with sarcopenia was also evaluated. A cut-off value for each index was reported to facilitate the diagnosis of patients with sarcopenia in a Korean population.
We used the 5th Korean National Health and Nutrition Examination Survey data from 2010. We analyzed 409 elderly patients, including 231 men and 178 women, aged ≥65 years. Patients were diagnosed by calculating their skeletal muscle index based on the skeletal muscle mass measured using dual energy X-ray absorptiometry. Obesity and osteoporosis were used to screen data and EuroQOL-5 dimension as a health questionnaire.
The prevalence of sarcopenia in each index was obtained based on its cut-off value for diagnosing sarcopenia. There was a significant difference between the obesity rate of elderly patients diagnosed with sarcopenia and those who were not based on each index. There was no significant difference in the prevalence of osteoporosis between the groups. Sarcopenia diagnosis based on the LESMI was significantly correlated with QOL.
LESMI, a novel index based on skeletal muscle mass, reflects changes in QOL and is appropriate for the body composition of elderly people in Korea.
我们试图开发一种基于骨骼肌质量的新型指数，该指数能够反映生活质量（QOL）的变化，并且是韩国老年人身体成分最合适的指数。我们还评估了下肢骨骼肌质量指数（LESMI）是否是诊断肌肉减少症患者的合适的新型指数。报告了每个指数的临界值，以促进对韩国人群中肌肉减少症患者的诊断。
我们使用了2010年韩国第五次全国健康与营养检查调查的数据。我们分析了409名年龄≥65岁的老年患者，其中包括231名男性和178名女性。通过基于使用双能X线吸收法测量的骨骼肌质量计算骨骼肌指数来诊断患者。使用肥胖和骨质疏松症来筛选数据，并使用欧洲五维健康量表作为健康调查问卷。
根据诊断肌肉减少症的临界值获得了每个指数中肌肉减少症的患病率。根据每个指数，被诊断为肌肉减少症的老年患者与未被诊断为肌肉减少症的老年患者的肥胖率之间存在显著差异。两组之间骨质疏松症的患病率没有显著差异。基于LESMI的肌肉减少症诊断与生活质量显著相关。
LESMI是一种基于骨骼肌质量的新型指数，反映了生活质量的变化，适用于韩国老年人的身体成分。
