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肌少症对老年人健康相关生活质量的影响:韩国国民健康营养调查。

The impact of sarcopenia on health-related quality of life in elderly people: Korean National Health and Nutrition Examination Survey.

机构信息

Department of Internal Medicine, College of Medicine, Uijeongbu St. Mary's Hospital, The Catholic University of Korea, Uijeongbu, Korea.

Clinical Research Coordinating Center, The Catholic University of Korea, Seoul, Korea.

出版信息

Korean J Intern Med. 2019 Jul;34(4):877-884. doi: 10.3904/kjim.2017.182. Epub 2017 Nov 27.

Abstract

BACKGROUND/AIMS: The purpose of the study is to investigate the associations between sarcopenia and health-related quality of life in elderly men and women in Korea.

METHODS

In a cross-sectional study using data from 2008 to 2011 Korean National Health and Nutrition Examination Survey, 4,937 adults aged 60 years and older who underwent a dual-energy X-ray absorptiometry scan were included in the study. Sarcopenia is defined as an appendicular skeletal muscle index of two standard deviations or more below the mean for young, healthy reference populations. The health-related quality of life was measured using the EuroQol-5 dimension questionnaire.

RESULTS

The overall prevalence of sarcopenia was 6.6% in these Korean people over the age of 60 years: 11.1% for men and 3.2% for women. Sarcopenic men tended to have lower income, lower physical activity, lower body mass index, and smaller waist circumference compared with nonsarcopenic men. Sarcopenic women tended to have higher body mass index and larger waist circumference compared with nonsarcopenic women. Sarcopenic men showed higher impairments in mobility, self-care, usual activities, and pain/discomfort compared with nonsarcopenic men. Women with sarcopenia also showed higher impairments in mobility, self-care, usual activities, and anxiety/depression compared with nonsarcopenic women. Sarcopenia showed an association with impairments in selfcare for men, and with impairments in self-care, usual activities, and anxiety/depression for women, after adjusting for other confounding factors.

CONCLUSION

There is a significant association between sarcopenia and impaired health-related quality of life in this elderly Korean population, and these results differ between men and women.

摘要

背景/目的:本研究旨在探讨韩国老年男女肌少症与健康相关生活质量之间的关系。

方法

本研究采用 2008 年至 2011 年韩国国家健康和营养调查的数据进行横断面研究,共纳入 4937 名年龄在 60 岁及以上并接受双能 X 线吸收法扫描的成年人。肌少症定义为四肢骨骼肌指数低于年轻健康参考人群平均值两个标准差或更多。健康相关生活质量采用欧洲五维健康量表问卷进行测量。

结果

这些 60 岁以上的韩国人总体肌少症患病率为 6.6%:男性为 11.1%,女性为 3.2%。与非肌少症男性相比,肌少症男性的收入较低、体力活动较少、身体质量指数较低、腰围较小。与非肌少症女性相比,肌少症女性的身体质量指数较高、腰围较大。肌少症男性在移动性、自理能力、日常活动和疼痛/不适方面的损伤程度高于非肌少症男性。肌少症女性在移动性、自理能力、日常活动和焦虑/抑郁方面的损伤程度也高于非肌少症女性。调整其他混杂因素后,肌少症与男性的自理能力受损以及女性的自理能力、日常活动和焦虑/抑郁受损相关。

结论

在这一老年韩国人群中,肌少症与健康相关生活质量受损之间存在显著关联,且这种关联在男性和女性中存在差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ffc/6610192/038c9cf99294/kjim-2017-182f1.jpg

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