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埃及儿童中的川崎病:病例系列

Kawasaki disease among Egyptian children: A case series.

作者信息

Attia Tarek Hamed, Morsy Saed M, Hassan Bashier A, Ali Al Shymaa A

机构信息

Pediatrics Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

出版信息

Glob Cardiol Sci Pract. 2017 Oct 31;2017(3):e201725. doi: 10.21542/gcsp.2017.25.

DOI:10.21542/gcsp.2017.25
PMID:29564346
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5856969/
Abstract

Kawasaki disease is an acute vasculitis of early childhood. Its incidence varies among different ethnic groups with higher rates among Asians. In this case series, we presented four cases of Kawasaki disease with incomplete or atypical presentations in Egyptian children. Two cases presented with meningitis, which is not a criteria for the diagnosis of Kawasaki disease. The other two cases presented with pharyngitis and fever, which did not respond to antibiotics. The clinical criteria for diagnosis of Kawasaki disease were either incomplete or appeared sequentially. Coronary artery aneurysms were detected in one case, while the others had normal coronary by echocardiography. All cases were followed in our clinic, according to international guidelines. Early diagnosis and management of Kawasaki disease are important to ensure a good outcome and a high index of suspicion in febrile children is required irrespective of the clinical presentation.

摘要

川崎病是一种儿童期的急性血管炎。其发病率在不同种族群体中有所差异,亚洲人的发病率较高。在本病例系列中,我们呈现了4例埃及儿童川崎病不完全或非典型表现的病例。2例表现为脑膜炎,这并非川崎病诊断标准中的一项。另外2例表现为咽炎和发热,对抗生素治疗无效。川崎病的临床诊断标准要么不完全,要么是相继出现。1例检测到冠状动脉瘤,而其他病例经超声心动图检查冠状动脉正常。所有病例均按照国际指南在我们诊所进行随访。川崎病的早期诊断和管理对于确保良好预后很重要,对于发热儿童,无论临床表现如何,都需要保持高度怀疑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0896/5856969/1b0565b3cc0d/gcsp-2017-3-e201725-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0896/5856969/5e19e66bb916/gcsp-2017-3-e201725-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0896/5856969/8eed2a451826/gcsp-2017-3-e201725-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0896/5856969/08bce720c84c/gcsp-2017-3-e201725-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0896/5856969/1b0565b3cc0d/gcsp-2017-3-e201725-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0896/5856969/5e19e66bb916/gcsp-2017-3-e201725-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0896/5856969/8eed2a451826/gcsp-2017-3-e201725-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0896/5856969/08bce720c84c/gcsp-2017-3-e201725-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0896/5856969/1b0565b3cc0d/gcsp-2017-3-e201725-g004.jpg

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本文引用的文献

1
Kawasaki Disease: A Clinician's Update.川崎病:临床医生最新指南
Int J Pediatr. 2013;2013:645391. doi: 10.1155/2013/645391. Epub 2013 Oct 27.
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Epidemiology of Kawasaki disease in Asia, Europe, and the United States.川崎病在亚洲、欧洲和美国的流行病学。
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Delayed diagnosis of Kawasaki disease: risk factors and outcome of treatment.川崎病的延迟诊断:危险因素及治疗结果
川崎病和与COVID-19相关的儿童多系统炎症综合征的神经学表现:两种不同临床实体的比较
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Value of NSE and S100 Protein of Kawasaki Disease with Aseptic Meningitis in Infant.婴儿川崎病合并无菌性脑膜炎时NSE和S100蛋白的价值
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