Gómez-Candela Carmen, Palma Milla Samara, Miján-de-la-Torre Alberto, Rodríguez Ortega Pilar, Matía Martín Pilar, Loria Kohen Viviana, Campos Del Portillo Rocío, Martín-Palmero Ángela, Virgili Casas M ª Nuria, Martínez Olmos Miguel Á, Mories Álvarez M ª Teresa, Castro Alija M ª José, Martín-Palmero Ángela
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Nutr Hosp. 2018 Mar 7;35(Spec No1):11-48. doi: 10.20960/nh.1561.
Anorexia nervosa is the most common psychiatric disease among young women and it is assumed to be of multifactorial origin. Diagnostic criteria have recently been modified; therefore amenorrhea has ceased to be a part of them. This disease shows a large variability in its presentation and severity which conditions different therapeutic approaches and the need to individualize the treatment, thus it is indispensable a multidisciplinary approach. The goals are to restore nutritional status (through an individualized diet plan based on a healthy consumption pattern), treat complications and comorbidities, nutritional education (based on healthy eating and nutritional patterns), correction of compensatory behaviors and relapse prevention. The treatment will vary according to the patient's clinical situation, and it may be performed in outpatient clinics (when there is clinical stability), in a day hospital or ambulatory clinic (intermediate mode between traditional outpatient treatment and hospitalization) or hospitalization (when there is outpatient management failure or presence of serious medical or psychiatric complications). Artificial nutrition using oral nutritional supplements, enteral nutrition and exceptionally parenteral nutrition may be necessary in certain clinical settings. In severely malnourished patients the refeeding syndrome should be avoided. Anorexia nervosa is associated with numerous medical complications which determines health status, life quality, and is closely related to mortality. There is little clinical evidence to assess the results of different treatments in anorexia nervosa, when most of the recommendations are being based on expert consensus.
神经性厌食症是年轻女性中最常见的精神疾病,其病因被认为是多因素的。诊断标准最近有所修改;因此,闭经不再是其中的一部分。这种疾病在表现和严重程度上有很大差异,这决定了不同的治疗方法以及个性化治疗的必要性,因此多学科方法必不可少。目标是恢复营养状况(通过基于健康消费模式的个性化饮食计划)、治疗并发症和合并症、进行营养教育(基于健康饮食和营养模式)、纠正代偿行为以及预防复发。治疗将根据患者的临床情况而有所不同,可能在门诊诊所进行(临床稳定时)、在日间医院或门诊诊所(传统门诊治疗和住院之间的中间模式)或住院治疗(门诊管理失败或存在严重医疗或精神并发症时)。在某些临床情况下,可能需要使用口服营养补充剂、肠内营养以及特殊情况下的肠外营养进行人工营养。在严重营养不良的患者中,应避免再喂养综合征。神经性厌食症与众多医学并发症相关,这些并发症决定了健康状况、生活质量,并且与死亡率密切相关。在评估神经性厌食症不同治疗结果时,临床证据很少,而大多数建议是基于专家共识。