Daniels Brodie, Reimers Penny, King Tracy, Schmidt Stefan, Coutsoudis Anna
1 Department of Paediatrics and Child Health, School of Clinical Medicine, University of KwaZulu-Natal , Durban, South Africa .
2 Discipline of Microbiology, School of Life Sciences, University of KwaZulu-Natal , Pietermaritzburg, South Africa .
Breastfeed Med. 2018 May;13(4):281-285. doi: 10.1089/bfm.2018.0017. Epub 2018 Mar 22.
PiAstra is a simulated flash-heat (FH) pasteurization temperature monitoring system designed using Raspberry Pi technology for the pasteurization of human milk. This study analyzed the effect of the PiAstra FH method on human milk immune components (immunoglobulin A [IgA] and lactoferrin activity).
Donor milk samples (N = 45) were obtained from a human milk bank, and pasteurized. Concentrations of IgA and lactoferrin activity were compared to their unpasteurized controls using the Student's t test.
The PiAstra FH method retained 34.2% of IgA (p < 0.0001) and 40.4% of lactoferrin activity (p < 0.0001) when compared to unpasteurized controls. The retention of IgA by the PiAstra is similar to previous FH studies, while retention of lactoferrin activity was higher than previous FH studies.
The high-technology, low-cost PiAstra system, which is able to retain vital immune components of human milk, provides safe donor milk for low-resourced settings. This enables the use of pasteurized donor milk when human milk is not available, potentially saving vulnerable infant lives.
PiAstra是一种模拟闪热（FH）巴氏杀菌温度监测系统，采用树莓派技术设计，用于人乳的巴氏杀菌。本研究分析了PiAstra FH方法对人乳免疫成分（免疫球蛋白A [IgA]和乳铁蛋白活性）的影响。
从人乳库获取供体乳样本（N = 45）并进行巴氏杀菌。使用学生t检验将IgA浓度和乳铁蛋白活性与其未巴氏杀菌的对照进行比较。
与未巴氏杀菌的对照相比，PiAstra FH方法保留了34.2%的IgA（p < 0.0001）和40.4%的乳铁蛋白活性（p < 0.0001）。PiAstra对IgA的保留率与之前的FH研究相似，而乳铁蛋白活性的保留率高于之前的FH研究。
高科技、低成本的PiAstra系统能够保留人乳的重要免疫成分，为资源匮乏地区提供安全的供体乳。这使得在无法获得人乳时能够使用巴氏杀菌的供体乳，有可能挽救脆弱婴儿的生命。
