a Center for Fundamental Education, Teikyo University of Science , Tokyo , Japan.
b Department of Health and Sport Science , Nippon Sport Science University , Tokyo , Japan.
Clin Exp Hypertens. 2019;41(2):123-129. doi: 10.1080/10641963.2018.1451535. Epub 2018 Mar 22.
The aim of this study was to investigate the acute repeated bouts of aerobic exercise decrease leg arterial stiffness. However, the influence of repeated bouts of aerobic exercise on arterial stiffness after glucose ingestion is unknown. The present study investigates the acute effects of repeated bouts of aerobic exercise on arterial stiffness after the 75-g oral glucose tolerance test (OGTT). Ten healthy young men (age, 23.2 ± 0.9 years) performed repeated bouts of aerobic exercise trial (RE, 65% peak oxygen uptake; two 15 min bouts of cycling performed 20 min apart) and control trial (CON, seated and resting in a quiet room) at 80 min before the 75-g OGTT on separate days in a randomized, controlled crossover fashion. Carotid-femoral (aortic) and femoral-ankle (leg) pulse wave velocity, carotid augmentation index, brachial and ankle blood pressure, heart rate and blood glucose and insulin levels were measured before (baseline) and 30, 60 and 120 min after the 75-g OGTT. Leg pulse wave velocity, ankle systolic blood pressure and blood glucose levels increased from baseline after the 75-g OGTT in the CON trial, but not in the RE trial. The present findings indicate that acute repeated bouts of aerobic exercise before glucose ingestion suppress increases in leg arterial stiffness following glucose ingestion. Abbreviations: RE trial repeated bouts of aerobic exercise trial; CON trial control trial; BG blood glucose; VO peak oxygen uptake; PWV Pulse wave velocity; AIx carotid augmentation index; BP blood pressure; HR heart rate; CVs coefficients of variation; RPE Ratings of perceived exertion; SE standard error.
本研究旨在探究急性重复有氧运动对腿部动脉僵硬度的影响。然而，反复进行有氧运动对葡萄糖摄入后动脉僵硬度的影响尚不清楚。本研究探讨了 75g 口服葡萄糖耐量试验（OGTT）后急性重复有氧运动对动脉僵硬度的影响。10 名健康年轻男性（年龄 23.2±0.9 岁）在 75g OGTT 前 80min 分别以随机对照交叉方式进行重复有氧运动试验（RE，65%峰值摄氧量；2 次 15min 踏车运动，间隔 20min）和对照试验（CON，安静室内坐姿和休息）。在 75g OGTT 前（基础状态）及之后 30、60 和 120min 时测量颈股（主动脉）和股踝（腿部）脉搏波速度、颈动脉增强指数、肱动脉和踝动脉血压、心率和血糖及胰岛素水平。在 CON 试验中，75g OGTT 后腿部脉搏波速度、踝部收缩压和血糖水平均高于基础值，但在 RE 试验中则无此变化。本研究结果表明，葡萄糖摄入前的急性重复有氧运动可抑制葡萄糖摄入后腿部动脉僵硬度的增加。缩写：RE 试验重复有氧运动试验；CON 试验对照试验；BG 血糖；VO 峰值摄氧量；PWV 脉搏波速度；AIx 颈动脉增强指数；BP 血压；HR 心率；CVs 变异系数；RPE 感觉用力程度评分；SE 标准误差。
