Kobayashi Ryota, Hashimoto Yuto, Okamoto Takanobu
Center for Fundamental Education, Teikyo University of Science, 2-2-1 Senju, Sakuragi, Adachi-ku, Tokyo 120-0045, Japan.
Graduate School of Health and Sport Science, Nippon Sport Science University, 7-1-1 Fukasawa, Setagaya-ku, Tokyo 158-8508, Japan.
J Clin Biochem Nutr. 2019 Mar;64(2):164-169. doi: 10.3164/jcbn.18-71. Epub 2019 Jan 16.
The present study investigated the acute effect of a footbath on increases in arterial stiffness after glucose ingestion in healthy young women. Nine healthy young women (aged 18.4 ± 0.2 years; mean ± SE) completed three trials in random order. They started a footbath before 75-g oral glucose ingestion, a footbath after 75-g oral glucose ingestion and no footbath (control) trials. Aortic (carotid-femoral) and leg (femoral-ankle) pulse wave velocity, the carotid augmentation index, carotid, brachial and ankle blood pressure, heart rate, blood glucose levels, insulin levels and sublingual temperature were measured before (baseline) and at 15, 30, 60 and 90 min after the 75-g oral glucose ingestion. Aortic pulse wave velocity and brachial systolic blood pressure did not change from baseline to after the 75-g oral glucose ingestion in all trials. Leg pulse wave velocity and ankle systolic blood pressure were increased from baseline to after the 75-g oral glucose ingestion in the footbath after glucose ingestion and control trials, but not in the footbath before glucose ingestion trial. These results suggest that a footbath effectively suppresses the increase in leg arterial stiffness after glucose ingestion when implemented before glucose ingestion.
本研究调查了足浴对健康年轻女性摄入葡萄糖后动脉僵硬度增加的急性影响。九名健康年轻女性（年龄18.4±0.2岁；均值±标准误）按随机顺序完成了三项试验。她们在口服75克葡萄糖之前开始足浴、在口服75克葡萄糖之后开始足浴以及不进行足浴（对照）试验。在口服75克葡萄糖之前（基线）以及之后的15、30、60和90分钟测量主动脉（颈动脉 - 股动脉）和腿部（股动脉 - 脚踝）脉搏波速度、颈动脉增强指数、颈动脉、肱动脉和脚踝血压、心率、血糖水平、胰岛素水平以及舌下温度。在所有试验中，从基线到口服75克葡萄糖之后，主动脉脉搏波速度和肱动脉收缩压均未发生变化。在口服葡萄糖后足浴试验和对照试验中，从基线到口服75克葡萄糖之后，腿部脉搏波速度和脚踝收缩压升高，但在口服葡萄糖之前足浴试验中未升高。这些结果表明，在摄入葡萄糖之前进行足浴可有效抑制摄入葡萄糖后腿部动脉僵硬度的增加。
