Food and Drug Administration, Ministry of Health and Welfare, Taipei, Taiwan.
J Food Drug Anal. 2018 Apr;26(2):565-571. doi: 10.1016/j.jfda.2017.06.008. Epub 2017 Jul 8.
Antibiotics have been widely used in the treatment of livestock diseases. However, the emergence of issues related to drug resistance prompted governments to enact a series of laws regulating the use of antibiotics in livestock. Following control of the problem of drug resistant bacteria, public attention has shifted to the recurring incidence of human health and safety issues caused by residual veterinary drugs in livestock products. To guarantee the safety and hygiene of meat, milk, and eggs from food-producing animals, governments and relevant agencies established laws and regulations for the use of veterinary drugs. It is, therefore, necessary to monitor the content of residual drugs in livestock products at regular intervals to assess whether the regulations have resulted in the effective management of food product safety, and to prevent and manage sudden problems related to this issue. A 2011-2015 livestock product post-marketing monitoring program launched by the Taiwan Food and Drug Administration (TFDA) inspected 1487 livestock products. Over the past 5 years, there were 34 samples identified that did not conform to the regulations; these samples included residue drugs such as β-agonists, chloramphenicols, β-lactam antibiotics, sulfa drugs, enrofloxacin, and lincomycin. Inspections of commercial livestock products with the consistent cooperation of agricultural authorities did not detect the drugs that were banned by the government, whereas the detection of other drugs decreased annually with an increase in the post-market monitoring sample size. In the future, the TFDA will continue to monitor the status of residual veterinary drugs in commercial livestock products, adjust the sampling of food products annually according to monitoring results, and closely cooperate with agricultural authorities on source management.
抗生素在治疗家畜疾病方面得到了广泛应用。然而,由于耐药性问题的出现,各国政府出台了一系列法规来规范抗生素在畜牧业中的使用。在控制耐药细菌问题之后,人们的注意力转向了畜产品中残留兽药对人类健康和安全问题的反复发生。为了保障食用动物肉类、奶和蛋类的安全和卫生,政府和相关机构制定了兽药使用的法律法规。因此,有必要定期监测畜产品中残留药物的含量,以评估这些规定是否有效管理了食品安全,并预防和管理与这一问题相关的突发问题。台湾食品药品监督管理局(TFDA)在 2011 年至 2015 年期间开展了一项畜产品上市后监测计划,共检测了 1487 个畜产品样本。在过去的 5 年中,有 34 个样本不符合规定,这些样本中包括β-激动剂、氯霉素、β-内酰胺类抗生素、磺胺类药物、恩诺沙星和林可霉素等残留药物。在农业部门的一致合作下,对商业畜产品的检查未发现政府禁止的药物,但随着上市后监测样本量的增加,其他药物的检测量逐年减少。未来,TFDA 将继续监测商业畜产品中残留兽药的状况,根据监测结果调整食品产品的抽样,与农业部门密切合作进行源头管理。