Rhoten Bethany Andrews, Murphy Barbara A, Dietrich Mary S, Ridner Sheila Hedden
Vanderbilt University School of Nursing, Nashville, Tennessee.
Department of Oncology, Vanderbilt Ingram Cancer Center, Nashville, Tennessee.
Head Neck. 2018 Jul;40(7):1443-1452. doi: 10.1002/hed.25129. Epub 2018 Mar 23.
This study examined the relationships of depressive symptoms and social anxiety with perceived neck function in patients treated for head and neck cancer.
Depressive symptoms, social anxiety, and perceived neck-related function were measured at baseline, posttreatment, every 6 weeks thereafter for 1 year after the end of treatment, and at 15 and 18 months posttreatment. Group-based trajectory modeling was used to generate clusters of patients with similar baseline and trajectories of perceived neck-related function after head and neck cancer treatment.
Participants included 83 subjects who had completed at least 1 follow-up assessment. Three clusters of longitudinal patterns in neck disability were identified: none/mild, moderate, and severe. Significant associations were found between membership in the neck disability index trajectories and membership in the longitudinal patterns of depressive symptoms and social anxiety.
Impaired physical function and psychological distress are intertwined for patients with head and neck cancer long after completing treatment.
本研究调查了接受头颈癌治疗的患者中抑郁症状和社交焦虑与颈部功能认知之间的关系。
在基线、治疗后、治疗结束后1年内每6周、治疗后15个月和18个月测量抑郁症状、社交焦虑和颈部相关功能认知。基于组的轨迹模型用于生成头颈癌治疗后具有相似基线和颈部相关功能认知轨迹的患者聚类。
参与者包括83名完成至少1次随访评估的受试者。确定了颈部残疾的三种纵向模式聚类:无/轻度、中度和重度。在颈部残疾指数轨迹的类别与抑郁症状和社交焦虑的纵向模式类别之间发现了显著关联。
头颈癌患者在完成治疗后的很长时间内,身体功能受损和心理困扰是相互交织的。