Institute for Biomedical Engineering, ETH Zurich and University of Zurich, Zurich, Switzerland.
Translational Neuromodeling Unit, Institute for Biomedical Engineering, University of Zurich and ETH Zurich, Zurich, Switzerland.
Magn Reson Med. 2018 Nov;80(5):1836-1846. doi: 10.1002/mrm.27176. Epub 2018 Mar 25.
The purpose of this work is to explore the feasibility and performance of single-shot spiral MRI at 7 T, using an expanded signal model for reconstruction.
Gradient-echo brain imaging is performed on a 7 T system using high-resolution single-shot spiral readouts and half-shot spirals that perform dual-image acquisition after a single excitation. Image reconstruction is based on an expanded signal model including the encoding effects of coil sensitivity, static off-resonance, and magnetic field dynamics. The latter are recorded concurrently with image acquisition, using NMR field probes. The resulting image resolution is assessed by point spread function analysis.
Single-shot spiral imaging is achieved at a nominal resolution of 0.8 mm, using spiral-out readouts of 53-ms duration. High depiction fidelity is achieved without conspicuous blurring or distortion. Effective resolutions are assessed as 0.8, 0.94, and 0.98 mm in CSF, gray matter and white matter, respectively. High image quality is also achieved with half-shot acquisition yielding image pairs at 1.5-mm resolution.
Use of an expanded signal model enables single-shot spiral imaging at 7 T with unprecedented image quality. Single-shot and half-shot spiral readouts deploy the sensitivity benefit of high field for rapid high-resolution imaging, particularly for functional MRI and arterial spin labeling.
本研究旨在探索 7T 单次激发螺旋 MRI 的可行性和性能,采用扩展信号模型进行重建。
在 7T 系统上进行梯度回波脑成像,采用高分辨率单次激发螺旋读取和半激发螺旋,在单次激发后进行双图像采集。图像重建基于包括线圈灵敏度、静态离频和磁场动力学的编码效果的扩展信号模型。后两者与图像采集同时记录,使用 NMR 场探头。通过点扩散函数分析评估所得图像分辨率。
采用 53ms 持续时间的螺旋读出技术,实现了名义分辨率为 0.8mm 的单次激发螺旋成像。无明显模糊或失真,实现了高的描绘保真度。在 CSF、灰质和白质中,有效分辨率分别评估为 0.8、0.94 和 0.98mm。半激发采集也能实现高质量的图像,得到 1.5mm 分辨率的图像对。
扩展信号模型的使用使得在 7T 下能够实现具有前所未有的图像质量的单次激发螺旋成像。单次激发和半激发螺旋读取利用高场的灵敏度优势实现快速高分辨率成像,特别适用于功能磁共振成像和动脉自旋标记。