Cardiovascular Internal Medicine, Yodogawa Christian Hospital, Osaka, Japan.
Faculty of Sports Sciences, Waseda University, Saitama, Japan.
ESC Heart Fail. 2018 Aug;5(4):586-591. doi: 10.1002/ehf2.12285. Epub 2018 Mar 25.
This study aimed to evaluate the impact of aerobic exercise training with vascular occlusion in patients with chronic heart failure.
Thirty patients with post-infarction heart failure were randomized to an interventional exercise group (IG; n = 15) or a control exercise group (CG; n = 15). Exercise was performed at an intensity of 40-70% of the peak VO /W for 6 months. Patients in the IG remained seated on the saddle of the cycle ergometer with their feet on the pedals. Pneumatic tourniquets were applied to the proximal ends of their thighs with appropriate pressure resulting in a 40-80 mmHg increase in the systolic blood pressure that is required for vascular occlusion (208.7 ± 7.4 mmHg). We evaluated the safety and efficacy of the intervention and its effect on exercise capacity and serum BNP levels. There were no significant differences between the IG and CG in patient characteristics at study entry. Peak VO /W in the IG significantly increased compared with that in the CG; the change in the serum BNP levels was significantly larger in the IG than in the CG.
These results suggest that aerobic exercise training with vascular occlusion can improve exercise capacity and serum BNP levels in patients with chronic heart failure.
本研究旨在评估伴有血管阻塞的有氧运动训练对慢性心力衰竭患者的影响。
30 例心肌梗死后心力衰竭患者随机分为干预运动组（IG；n=15）和对照运动组（CG；n=15）。运动强度为峰值 VO /W 的 40-70%，持续 6 个月。IG 患者坐在自行车测力计的鞍座上，双脚放在踏板上。气压止血带应用于大腿近端，施加适当的压力，使收缩压升高 40-80mmHg，达到血管阻塞所需的压力（208.7±7.4mmHg）。我们评估了干预措施的安全性和疗效，以及其对运动能力和血清 BNP 水平的影响。在研究开始时，IG 和 CG 患者的特征无显著差异。IG 组的峰值 VO /W 明显高于 CG 组；IG 组的血清 BNP 水平变化明显大于 CG 组。
这些结果表明，伴有血管阻塞的有氧运动训练可以改善慢性心力衰竭患者的运动能力和血清 BNP 水平。
