Rimbert Sébastien, Al-Chwa Rahaf, Zaepffel Manuel, Bougrain Laurent
Neurosys team, Inria, Villers-lès-Nancy, France.
Artificial Intelligence and Complex Systems, Université de Lorraine, LORIA, Vandœuvre-lès-Nancy, France.
PeerJ. 2018 Mar 15;6:e4492. doi: 10.7717/peerj.4492. eCollection 2018.
There is fundamental knowledge that during the resting state cerebral activity recorded by electroencephalography (EEG) is strongly modulated by the eyes-closed condition compared to the eyes-open condition, especially in the occipital lobe. However, little research has demonstrated the influence of the eyes-closed condition on the motor cortex, particularly during a self-paced movement. This prompted the question: How does the motor cortex activity change between the eyes-closed and eyes-open conditions? To answer this question, we recorded EEG signals from 15 voluntary healthy subjects who performed a simple motor task (i.e., a voluntary isometric flexion of the right-hand index) under two conditions: eyes-closed and eyes-open. Our results confirmed strong modulation in the mu rhythm (7-13 Hz) with a large event-related desynchronisation. However, no significant differences have been observed in the beta band (15-30 Hz). Furthermore, evidence suggests that the eyes-closed condition influences the behaviour of subjects. This study gives us greater insight into the motor cortex and could also be useful in the brain-computer interface (BCI) domain.
有基础知识表明，在静息状态下，与睁眼状态相比，脑电图（EEG）记录的大脑活动在闭眼状态下受到强烈调制，尤其是在枕叶。然而，很少有研究证明闭眼状态对运动皮层的影响，特别是在自主运动期间。这引发了一个问题：运动皮层活动在闭眼和睁眼状态之间如何变化？为了回答这个问题，我们记录了15名自愿参与的健康受试者在两种状态下（闭眼和睁眼）执行简单运动任务（即右手食指的自主等长屈曲）时的EEG信号。我们的结果证实了在μ节律（7-13Hz）中有强烈调制，伴有大量事件相关去同步化。然而，在β波段（15-30Hz）未观察到显著差异。此外，有证据表明闭眼状态会影响受试者的行为。这项研究让我们对运动皮层有了更深入的了解，也可能在脑机接口（BCI）领域有用。
