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机器人辅助胰十二指肠切除术:单术者初始经验

Robotic Pancreaticoduodenectomy: Single-Surgeon Initial Experience.

作者信息

Wang Mingjun, Cai Yunqiang, Li Yongbin, Peng Bing

机构信息

Department of Pancreatic Surgery, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Chengdu, Sichuan 610041 China.

出版信息

Indian J Surg. 2018 Feb;80(1):42-47. doi: 10.1007/s12262-016-1555-1. Epub 2016 Oct 21.

Abstract

Minimally invasive surgery has gained increasing acceptance over the last few years, which has expanded to pancreaticoduodenectomy. Laparoscopic pancreaticoduodenectomy has been determined to be a feasible, safe, and effective procedure in an experienced surgeon's hands, but the adaptations to the clumsy instruments are needed. The improved dexterity of the Da Vinci robotic system provides a good opportunity to perform this challenging procedure in the minimally invasive context. The aim of this study was to share our preliminary experience of totally robotic pancreaticoduodenectomy. From April 2015 to August 2015, four patients were selected to undergo totally robotic pancreaticoduodenectomy in the Department of Pancreatic Surgery, West China Hospital, Sichuan University, China. The demographic characteristics, perioperative details, and pathological results were retrospectively reviewed. One female and two male patients underwent totally robotic pancreaticoduodenectomy, while another male patient underwent robotic total pancreatectomy due to the severe atrophy of pancreatic body and tail. The mean age of the four patients was 56.8 years. The average operation time and intraoperative blood loss were 563 min and 228 mL, respectively. No one needed blood transfusion, conversion to open pancreaticoduodenectomy, or postoperative analgesia. The postoperative courses of these patients were uneventful. The mean postoperative hospital stay was 10 days. No one required to be readmitted, and there was no death within 30 days following the surgery. Final pathologic examinations revealed one malignant pancreatic ductal adenocarcinoma, and three benign lesions. Based on this initial study, robotic pancreaticoduodenectomy is safe and feasible, with acceptable oncological outcomes for highly selected patients in experienced surgeons' hands. However, concerns such as long-term outcomes, cost-effectiveness analysis, and learning curve analysis should be fully demonstrated before the popularization of this challenging procedure.

摘要

在过去几年中,微创手术越来越被广泛接受,其应用范围已扩展到胰十二指肠切除术。腹腔镜胰十二指肠切除术已被证实,在经验丰富的外科医生手中是一种可行、安全且有效的手术,但需要适应笨拙的器械。达芬奇机器人系统灵活性的提高,为在微创环境下进行这一具有挑战性的手术提供了良好机会。本研究的目的是分享我们在全机器人胰十二指肠切除术方面的初步经验。2015年4月至2015年8月,四川大学华西医院胰腺外科选取4例患者接受全机器人胰十二指肠切除术。回顾性分析了患者的人口统计学特征、围手术期细节及病理结果。1例女性和2例男性患者接受了全机器人胰十二指肠切除术,另1例男性患者因胰体尾严重萎缩接受了机器人全胰切除术。4例患者的平均年龄为56.8岁。平均手术时间和术中失血量分别为563分钟和228毫升。无人需要输血、中转开腹胰十二指肠切除术或术后镇痛。这些患者的术后病程顺利。术后平均住院时间为10天。无人需要再次入院,术后30天内无死亡病例。最终病理检查显示1例恶性胰腺导管腺癌和3例良性病变。基于这项初步研究,机器人胰十二指肠切除术是安全可行的,在经验丰富的外科医生手中,对于经过严格筛选的患者具有可接受的肿瘤学结局。然而,在推广这一具有挑战性的手术之前,应充分阐明诸如长期结局、成本效益分析和学习曲线分析等问题。

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