The Brain Institute, University of Utah, 383 Colorow Drive, Salt Lake City, UT 84108, USA.
Diagnostic Neuroimaging Lab, University of Utah, 501 Chipeta Way, Salt Lake City, UT 84108, USA.
Biomed Res Int. 2018 Feb 8;2018:8142631. doi: 10.1155/2018/8142631. eCollection 2018.
A number of studies have suggested that sports-related concussion (SRC) may place individuals at increased risk for depression and negative outcomes including suicide. However, the mechanisms underlying a potential relationship between brain integrity and mood remain unclear. The current study is aimed at examining the association between amygdala shape, mood state, and postconcussion symptoms in collegiate football players. Thirty members of 1 football team completed the Profile of Mood States (POMS), the postconcussion symptom scale (PCSS), and an MRI protocol during preseason camp. T1-weighted images were acquired and three-dimensional amygdala and probabilistic maps were created for shape analysis. Correlation analyses between POMS and PCSS and the relationship between POMS and amygdala shape were completed. In the amygdala, the left laterobasal subregion showed a positive relationship with the POMS total score and subscales scores. No significant relationship between PCSS and amygdala shape was found. Significant positive correlations were found between POMS subscales and PCSS. These results indicate that amygdala structure may be more closely associated with negative mood states than postconcussion symptoms. These findings suggest that premorbid individual differences in effect may provide critical insight into the relationship between negative mood and outcomes in collegiate football players with SRC.
一些研究表明，与运动相关的脑震荡（SRC）可能会使个体面临更高的抑郁风险和负面后果，包括自杀。然而，大脑完整性和情绪之间潜在关系的机制仍不清楚。本研究旨在研究大学生足球运动员的杏仁核形状、情绪状态和脑震荡后症状之间的关系。一个足球队的 30 名成员在季前训练营期间完成了《心境状态量表》（POMS）、脑震荡后症状量表（PCSS）和 MRI 方案。采集 T1 加权图像并创建三维杏仁核和概率图以进行形状分析。完成了 POMS 和 PCSS 之间的相关性分析以及 POMS 和杏仁核形状之间的关系。在杏仁核中，左侧基底外侧亚区与 POMS 总分和子量表评分呈正相关。未发现 PCSS 和杏仁核形状之间存在显著关系。POMS 子量表与 PCSS 之间存在显著正相关。这些结果表明，杏仁核结构可能与负面情绪状态的关系比脑震荡后症状更密切。这些发现表明，在 SRC 的大学生足球运动员中，情绪与结局之间的关系可能受到个体差异的影响。
