Ziegler M G, Shackford S R, Wilner K D, Norton C H
University of California Medical Center, San Diego 92103.
Experientia. 1987 Sep 15;43(9):1021-2. doi: 10.1007/BF01952226.
Atrial natriuretic factor (ANF) is released in response to many stimuli which increase right atrial pressure. Following hemorrhage pigs lowered their atrial pressures, developed a tachycardia and increased ANF levels. Electrical pacing increased heart rate and ANF levels. There is a stimulus to ANF release other than atrial stretch, probably heart rate.