Hofmeyr G J, Joffe M I, Bezwoda W R, van Iddekinge B
Department of Obstetrics and Gynaecology, Johannesburg Hospital, South Africa.
Fertil Steril. 1987 Oct;48(4):681-4. doi: 10.1016/s0015-0282(16)59486-2.
A significant association was found between absence of cytotoxicity to husbands' lymphocytes and of MLC suppression, both of which were absent more commonly in primary than secondary abortion. Following immunization with husbands' leukocytes, systemic side effects were common and cytotoxicity became positive in all but two of eight women tested, both of whom also failed to develop MLC suppression.
发现对丈夫淋巴细胞无细胞毒性与混合淋巴细胞培养抑制之间存在显著关联，在原发性流产中，这两种情况比继发性流产中更常见。在用丈夫的白细胞进行免疫后，全身副作用很常见，在接受测试的8名女性中，除两名女性外，其他所有人的细胞毒性都呈阳性，而这两名女性也未能产生混合淋巴细胞培养抑制。
