Winsor T, Haumschild D J, Winsor D W, Wang Y, Luong T N
University of Southern California School of Medicine, Los Angeles.
Angiology. 1987 Oct;38(10):727-36. doi: 10.1177/000331978703801001.
The cutaneous laser Doppler device (LDF) was employed to determine its usefulness in differentiating the circulation of the feet in normal subjects from that in patients with arteriosclerosis obliterans. It is shown that the laser Doppler frequencies correlated well with results from venous occlusion plethysmography, which measured volume rate of flow. Thus, one can determine volume rate of flow by the simple Doppler method. There was a linear relationship between these two methods of measurements. Using the LDF method, it was determined that normal individuals have toe flows that on the average are 42% of finger flows in supine resting subjects. In peripheral vascular disease of the lower extremities, the LDF measurements showed a decreased circulation in the large toes when the patients are supine and the lower extremities flat. The results between health and disease are exaggerated by elevating the feet, at which time the diseased circulation falls to extremely low values compared with those of normal subjects. A similar decrease in skin oxygen tension in the diseased lower extremities was observed when the limbs were elevated.
使用皮肤激光多普勒仪（LDF）来确定其在区分正常受试者与闭塞性动脉硬化患者足部血液循环方面的效用。结果表明，激光多普勒频率与静脉阻塞体积描记法（测量血流体积速率）的结果密切相关。因此，可以通过简单的多普勒方法确定血流体积速率。这两种测量方法之间存在线性关系。使用LDF方法确定，在仰卧休息的正常个体中，脚趾血流量平均为手指血流量的42%。在下肢外周血管疾病中，当患者仰卧且下肢平放时，LDF测量显示大脚趾的血液循环减少。抬高足部会使健康与疾病之间的结果差异更加明显，此时患病部位的血液循环与正常受试者相比降至极低值。当肢体抬高时，患病下肢的皮肤氧张力也出现类似下降。
