Kim Hyun-Chung, Yoo So-Young, Lee Bun-Hee, Lee So Hee, Shin Hyoung-Shik
Department of Psychiatry, National Medical Center, Seoul, Republic of Korea.
Maum & Maum Psychiatric Clinic, Seoul, Republic of Korea.
Psychiatry Investig. 2018 Apr;15(4):355-360. doi: 10.30773/pi.2017.10.25.1. Epub 2018 Mar 30.
Little is known about the psychiatric complications or risk factors for depression in suspected or confirmed Middle East Respiratory Syndrome (MERS) patients quarantined in hospital.
A retrospective chart review was performed of all the patients admitted to the acute MERS inpatient unit at the NMC during the 2015 outbreak.
30 (75%) were confirmed to be MERS-CoV positive among 40 admitted cases. Among the 24 MERS survivors, 17 (70.8%) exhibited psychiatric symptoms and 10 (41.7%) received a psychiatric diagnosis and medication during their hospital stay. Suspected MERS patients did not exhibit psychiatric symptoms or receive a psychiatric diagnosis. 27 suspected or confirmed MERS patients (age 41.15±18.64, male 37.0%) completed psychological assessments. A multiple linear regression analysis revealed that the Korean National Health and Nutrition Examination Survey-Short form and the Impact of Event Scale-Revised scores were significantly positively correlated with Patient Health Questionnaire-9 scores.
Our findings indicate that the acute treatment of MERS-CoV infections in quarantine had a significant impact on the patients' mental health. Furthermore, assessment of the risk factors for depression may identify vulnerable patients who require psychiatric care and attention during hospital quarantine.
对于在医院接受隔离的疑似或确诊中东呼吸综合征（MERS）患者的精神并发症或抑郁症风险因素，我们了解甚少。
对2015年疫情期间在NMC急性MERS住院部收治的所有患者进行回顾性病历审查。
40例收治病例中，30例（75%）确诊为MERS-CoV阳性。在24例MERS幸存者中，17例（70.8%）在住院期间出现精神症状，10例（41.7%）接受了精神科诊断并用药。疑似MERS患者未出现精神症状或接受精神科诊断。27例疑似或确诊MERS患者（年龄41.15±18.64，男性占37.0%）完成了心理评估。多元线性回归分析显示，韩国国民健康与营养检查调查简表和事件影响量表修订版得分与患者健康问卷-9得分显著正相关。
我们的研究结果表明，隔离状态下对MERS-CoV感染的急性治疗对患者心理健康有显著影响。此外，对抑郁症风险因素的评估可能有助于识别在医院隔离期间需要精神科护理和关注的脆弱患者。
